We studied 228 consecutive stem cell transplant recipients, screened for reactivation of human herpesvirus-6 (HHV-6) in peripheral blood and other specimens as clinically indicated by means of qualitative polymerase chain reaction. Among them, 197 received an allograft and 31 autograft. Ninety-six of 228 patients (42.1%) showed HHV-6 reactivation in peripheral blood and 129 of 228 (56.6%) demon...

BACKGROUND/AIMS Synchronous/metachronous gastric epithelial neoplasias (GENs) in the remaining lesion can develop at sites other than the site of endoscopic resection. In the present study, we aimed to investigate the predictive value of serum pepsinogen for detecting multiple GENs in patients who underwent endoscopic resection. METHODS In total, 228 patients with GEN who underwent endoscopic...

[1] We conducted 228-year long, three-member ensemble simulations using a high resolution (60 km grid size) global atmosphere model, MRI-AGCM3.2, with prescribed sea surface temperature and greenhouse gases and aerosols from 1872 to 2099. We found a clear decreasing trend of global tropical cyclone (TC) frequency throughout the 228 years of the simulation. We also found a significant multidecad...

The NMR structures of the recombinant human prion protein, hPrP(23-230), and two C-terminal fragments, hPrP(90-230) and hPrP(121-230), include a globular domain extending from residues 125-228, for which a detailed structure was obtained, and an N-terminal flexibly disordered "tail." The globular domain contains three alpha-helices comprising the residues 144-154, 173-194, and 200-228 and a sho...

PURPOSE Aromatase inhibitors (AIs) have been recently associated with hip fractures. We present a case series of breast cancer survivors and a systematic review of bone health care in breast cancer. EXPERIMENTAL DESIGN We completed clinical assessments and bone density testing (BMD) of hip fractures from January 2005 to December 2008. Prefracture and 12-month functional status was obtained. S...

The biotyping scheme of Baird-Parker was applied to cultures of Staphylococcus epidermidis from patients. In all, 63.6% of 228 cultures belonged to biotype 1, followed by biotypes 4, 3, and 2 in decreasing order of incidence. When classified according to clinical source of isolation, cultures of S. epidermidis were most frequently isolated from urine, with 39.5% of 228 cultures from this source...

MARY A retrospective study of 228 consecutive carotid endctomies was conducted to determine the operative stroke and lity rate in two 600-bed community hospitals. The combined -mortality rate for the series was 21.1% (48 of 228). Eleven :erectomies were performed for asymptomatic bruits and the ned stroke-mortality rate was 18.2% (2 of 11). Fifty-seven endctomies were performed for transient is...

We investigate the proposal that integrins and focal adhesion kinase (FAK) form a complex that has structural and signaling functions in eggs. FAK protein is present in eggs and is phosphorylated at fertilization. pY(397)FAK localizes to the membrane 30 min after fertilization, which correlates with the expression of βC integrins and egg cortex development. The βC integrin and pY(397)FAK coimmu...

Aims: To evaluate the utility of endoscopic obliterative therapy with n-butyl-2-cyanoacrylate (tissue adhesives) for gastrointestinal varices and to investigate the incidence of serious complications. Methods: Endoscopic obliterative therapy with n-butyl-2-cyanoacrylate was performed on 228 gastrointestinal variceal patients; 221 gastric varices, 5 duodenal varices, and 2 anastomotic varices af...