Lysyl oxidase (LOX) is a copper-dependent amine oxidase that plays a critical role in pulmonary fibrosis. Our previous study demonstrated that epithelial-to-mesenchymal transition (EMT) was strongly associated with paraquat (PQ) induced pulmonary fibrosis. This present study was aimed to evaluate the potential involvement of LOX on EMT in the process of pulmonary fibrosis induced by PQ. We esta...

Epidemiological and in vivo studies have demonstrated that exposure to the pesticides paraquat (PQ) and maneb (MB) increase the risk of developing Parkinson's disease (PD) and cause dopaminergic cell loss, respectively. PQ is a well-recognized cause of oxidative toxicity; therefore, the purpose of this study was to determine if MB potentiates oxidative stress caused by PQ, thus providing a mech...

Praziquantel (PQ), a tetrahydroquinoline derivative, is a new and clinically effective antischistosomal drug, which has been shown to lack or to possess very weak mutagenic activity. However, in bacteria, this compound can act as a weak comutagen that increases the mutagenicity of several chemical mutagens and carcinogens. We have found that PQ can act as a very weak comutagen in animal cells. ...

Computer vision researchers have developed various learning methods based on the bag of words model for image related tasks, including image categorization, image retrieval and texture classification. In this model, images are represented as histograms of visual words (or textons) from a vocabulary that is obtained by clustering local image descriptors. Next, a classifier is trained on the data...

A B S T R A C T Perturbed Quantization (PQ) steganography scheme is almost undetectable with the current steganalysis methods. We present a new steganalysis method for detection of this data hiding algorithm. We show that the PQ method distorts the dependencies of DCT coefficient values; especially changes much lower than significant bitplanes. For steganalysis of PQ, we propose features extrac...

Power quality (PQ) has become a key problem of urban power grid recently. Improving power quality is a technical problem being concerned by both power supply companies and the consumers. Shenzhen power grid, as a typical urban power grid, is exemplified in this paper. Through researches, typical PQ issues of a key region in urban power grid are discussed. Industrial feasibility study is carried...

In this paper design and synthesis of a scaffold comprising primaquine (PQ) motif and cinnamic acid derivatives (CADs) bound directly (compounds 3a-k) or via a spacer (compounds 7a-k) are reported. In the first series of compounds, PQ and various CADs were connected by amide bonds and in the second series by acylsemicarbazide functional groups built from the PQ amino group, CONHNH spacer and th...

We consider two data-structuring problems which involve performing priority queue (pq) operations on a set of integers in the range 0 . . 2 − 1 on a unit-cost RAM with word size w bits. A monotone min-PQ has the property that the minimum value stored in the pq is a non-decreasing function of time. We give a monotone minpq that, starting with an empty set, processes a sequence of n insert and de...

The current interest in malaria elimination has led to a renewed interest in drugs that can be used for mass administration to minimize malaria transmission. Primaquine (PQ) is the only generally available drug with a strong activity against mature Plasmodium falciparum gametocytes, the parasite stage responsible for transmission. Despite concerns about PQ-induced hemolysis in glucose-6-phospha...

Background: Poisoning with paraquat (PQ) is highly fatal. In this study; demographic and clinical characteristics of  a series of patients with acute PQ poisoning treated at two university hospitals in Shiraz, Iran are presented and predictive factors for mortality are analyzed. Methods: This was an analytical cross-sectional study on consecutive PQ poisoned patients admitted to Shoushtari and ...