Agricultural residues Castanea mollissima shells represent a promising resource for natural pigments for the food industry. This study provides a comprehensive and systematic evaluation of water-soluble pigments (CSP) from C. mollissima shells, which were obtained by 50% ethanol with microwave-assisted extraction. Spectroscopic techniques (UV, FT-IR, (13)C NMR), elemental analysis, and chromato...

In Caenorhabditis elegans, apoptosis in germ cells is mediated by the same core apoptotic machinery that controls apoptosis in somatic cells. These include the CED-3 caspase, the CED-3 activator CED-4, and the cell death inhibitor CED-9. However, germline apoptosis also differs from somatic apoptosis in its regulation. We found that CSP-3, a caspase homolog that blocks CED-3 autoactivation and ...

The constrained shortest path (CSP) problem requires the determination of a minimum cost s-t path with delay at most a nonzero integer T. In this paper, we first point out the equivalence of certain algorithms, simply called the LARAC (Lagrangian Relaxation Based Aggregated Cost) algorithm presented independently in some earlier works. The LARAC algorithm solves the integer relaxation of the CS...

Objective: Cutaneous silent period (CSP) is an inhibitory spinal reflex and the afferent arm of this response involves A-delta nerve fibers. The aim of this study was to investigate CSP parameters in patients with type 2 diabetes mellitus (T2DM) and to examine the effects of alpha-lipoic acid (ALA) treatment on CSP. To the best of our knowledge, this investigation has not yet been carried out u...

Timed CSP can be used to model and analyse real-time and concurrent behaviour of embedded control systems. Practical CSP implementations combine the CSP model of a real-time control system with prioritized scheduling to achieve efficient and orderly use of limited resources. Schedulability analysis of a timed CSP model of a system with respect to a scheduling scheme and a particular execution p...

Animals perceiving repeated aversive events can become chronically stressed. Chronic activation of the hypothalamic-pituitary-adrenal (HPA) axis can have deleterious consequences on physiological parameters (e.g. BW, blood chemistry) and behaviour (e.g. emotional reactivity, stereotypies, cognition). Environmental enrichment (EE) can be a mean to reduce animal stress and to improve welfare. The...

Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder and is triggered via abnormal accumulation of amyloid-β peptide (Aβ). Aggregated Aβ is responsible for disrupting calcium homeostasis, inducing neuroinflammation, and promoting neurodegeneration. In this study, we generated curcuminoid submicron particle (CSP), which reduce the average size to ~60 nm in diameter. CSP had ...

When we want to use brain-computer interfaces (BCI) as an input modality for gaming, a short setup procedure is necessary. Therefore a user model has to be learned using small training sets. The common spatial patterns (CSP) algorithm is often used in BCI. In this work we investigate how the CSP algorithm generalizes when using small training sets, how the performance changes over time, and how...

Cisplatin (CSP) is a chemotherapeutic agent commonly used to treat a variety of malignancies. The major setback with CSP treatment is that its clinical efficacy is compromised by its induction of organ toxicity, particular to the kidneys and ears. Despite the significant strides that have been made in understanding the mechanisms underlying CSP-induced renal toxicity, advances in developing ren...

The process algebra Csp [1] [4] [15] [16] is a formal method devoted to the modelling as well as to the analysis and verification of concurrent systems. It is a speciality of Csp that it captures both, the concurrent system as well as its desired properties, as specifications: Let Sys be the formal Csp model of a concurrent system, let P be a property formulated in Csp – such a property could, ...