S ince the approval of tissue-type plasminogen activator (tPA) for the treatment of acute ischemic stroke by the Food and Drug Administration, 1 the search for means to identify patients who may benefit from this treatment beyond the approved therapeutic window has been actively pursued. One of the most successful examples is the European Cooperative Acute Stroke Study III (ECASS III) trial, 2,...

BIBW 22, a phenylpteridine analogue of dipyridamole (DPM), en hanced » ini risiine cytotoxicity approximately 10 times more than DPM in a multidrug-resistant (MDR) KB V20C cell line. Using rhodamine 123 accumulation in KB V20C cells as an indicator of MDR phenotype, BIBW 22 was shown to be about 100 times more potent than DPM in inhibiting the MDR-associated efflux of rhodamine 123. Photolabel...

Business Process Redesign (BPR) projects are considered to be high risk due to their high management complexity, enterprisewide impact, and steep project cost. This paper describes a technique that should reduce that risk by developing a systematic process redesign method that we call Dynamic Process Modeling (DPM). It integrates customer-oriented process modeling with computerized visual proce...

The chemical element krypton, whose principal source is the atmosphere, had a long-lived radioactive content, in the mid-1940s, of less than 5 dpm per liter of krypton. In the late 1940s, this content had risen to values in the range of 100 dpm per liter. It is now some hundred times higher than the late 1940 values. This radioactivity is the result of the dissolving of nuclear fuel for militar...

Dynamic Programming Matching (DPM) is a mathematical optimization technique for sequentially structured problems, which has, over the years, played a major role in providing primary algorithms in pattern recognition fields. Most practical applications of this method in signature verification have been based on the practical implementational version proposed by Sakoe and Chiba [1], and is usuall...

Dynamic power management (DPM) is a power reduction technique based on dynamically reconfiguring the systems to provide the requested services with a minimum load on the components of the system. DPM includes a set of techniques that achieves energy-efficient computation by selectively turning off (or reducing the performance of) system components when they are idle (or partially unexploited). ...

Yes, Lawrence DiDomenico, DPM, says technological advances with internal fixation may reduce the need for external fixation. He notes that ex-fix may not be as cost-effective as AO techniques in facilitating early weightbearing, and also cites the anesthesia risks associated with external fixation. No, George Vito, DPM, says that fixators can provide sufficient osseous stability to facilitate b...

In this paper we compare systematically the two-component Dual Parton Model (DPM) event generator Dpm-jet-III to d-Au and p–p data from RHIC. In this process we are able to improve the model. The need for fusion of chains and a recalibration of the model to obtain collision scaling in h-A and d-A collisions was found already in previous comparisons. Here, comparing to transverse momentum distri...

Os problemas de saúde mental são causadores morbidades em todo mundo. Dados da OMS estimam que existam cerca um bilhão pessoas atingidas por essa condição. distúrbios psíquicos menores (DPM) caracterizados sintomas como a ansiedade, fadiga, preocupação somática, depressão, insônia, irritabilidade e déficit memória concentração. Esses impactam negativamente no sono. O presente estudo caracteriza...