BACKGROUND AND OBJECTIVE Persistent hepatic progenitor cells (HPC) activation resulting in ductular reaction (DR) is responsible for pathologic liver repair in cholangiopathies. Also, HPC/DR expansion correlates with fibrosis in several chronic liver diseases, including steatohepatitis. Increasing evidence indicates Notch signaling as a key regulator of HPC/DR response in biliary and more in ge...

Many HPC applications suffer from a bottleneck in the shared caches, instruction execution units, I/O or memory bandwidth, even though remaining resources may be underutilized. It is hard for developers and runtime systems to ensure that all critical are fully exploited by single application, so an attractive technique increasing system utilization colocate multiple on same server. When share r...

Virtualization Technology is an interesting research topic in current cloud computing and service. Using the Virtualization Technology in cloud or cluster computing can obtain a lot of benefits, such as ability to deploy any virtual platforms rapidly, easiness to manage all precious resources, and cost reduction. In order to discover optimal performance for virtual platforms, several well-known...

The emergence of virtualization enabled hardware, such as the latest generation AMD and Intel processors, has raised significant interest in High Performance Computing (HPC) community. In particular, system-level virtualization provides an opportunity to advance the design and development of operating systems, programming environments, administration practices, and resource management tools. Th...

Damage to the hippocampus (HPC) using the excitotoxin N-methyl-D-aspartate (NMDA) can cause retrograde amnesia for contextual fear memory. This amnesia is typically attributed to loss of cells in the HPC. However, NMDA is also known to cause intense neuronal discharge (seizure activity) during the hours that follow its injection. These seizures may have detrimental effects on retrieval of memor...

The role of proteinases in the mobilization of hematopoietic progenitor cells (HPCs) after granulocyte colony-stimulating factor (G-CSF) remains unclear. Here we report that genetic loss of the plasminogen activator inhibitor Pai-1 or of the plasmin inhibitor alpha2-antiplasmin increases HPC mobilization in response to G-CSF. Moreover, thrombolytic agents, such as tenecteplase and microplasmin,...

AMA Reimisz P. EFFECT OF ZERO CALORIE DRINKS ON SENSORY-SPECIFIC SATIETY. Health Problems of Civilization. 2023. doi:10.5114/hpc.2023.127590. APA Reimisz, (2023). https://doi.org/10.5114/hpc.2023.127590 Chicago Patryk. "EFFECT SATIETY". Harvard MLA SATIETY." Civilization, Vancouver

The HPC2/ELAC2 gene on chromosome 17p was recently identified as a candidate gene for hereditary prostate cancer (HPC). To confirm these findings, we screened 300 prostate cancer patients (2 affected members/family) from 150 families with HPC for potential germ-line mutations using conformation-sensitive gel electrophoresis, followed by direct sequence analysis. The minimum criteria for our fam...