BACKGROUND Broad inhibition of matrix metalloproteinases (MMPs) attenuates left ventricular remodeling after myocardial infarction (MI). However, it is not clear if selective MMP inhibition strategies will be effective or if MMP inhibition will impair angiogenesis after MI. METHODS AND RESULTS We used a selective MMP inhibitor (MMPi) that does not inhibit MMP-1 in rabbits, which, like humans ...

The amnesic population provides a unique opportunity to examine the reliability of clinical tests because amnesics do not consciously recollect initial testing sessions. In this study, amnesic subjects were studied to examine the reliability between the Minnesota Multiphasic Personality Inventory (MMPI) and the MMPI-2. Findings indicated that there were no statistical differences between versio...

The comparative validity of Minnesota Multiphasic Personality Inventory—2 (MMPI-2) scores for African American (« = 123) and Caucasian (n = 561) clients from a community mental health center was investigated by contrasting mean MMPI-2 scores and correlations between those scores and conceptually related therapist rating scales for the 2 groups. The African American men scored significantly high...

Both the Minnesota Multiphasic Personality Inventory–2 (MMPI–2; Butcher et al., 2001) and Personality Assessment Inventory (PAI; Morey, 1991) offer a large set of scales devoted to the identification of response styles. This study directly compared the effectiveness of the 2 inventories as indicators of overreporting. The 2 measures were administered to 52 college students instructed to fake ba...

Psychiatric hospital records of 182 adult females were reviewed to determine feasibility of using the MMPI to uncover repressed histories of childhood abuse. Charts with MMPI profiles that met the standard and extended Scarlett O'Hara V configurations were examined for histories of childhood sexual or physical abuse and exposure to parental alcoholism. Findings were compared with a representati...

MMPI-2 maintains an extensive empirical base with psychiatric populations, although more recently, neurologically compromised patients have documented unique elevation patterns. This study examined mild-moderate TBI patients, Alzheimer's Dementia patients, and Psychiatric controls on MMPI-2 scales. Participants included 160 outpatients (TBI n = 26, AD n = 74, Psychiatric n = 60). Controlling fo...

The association between scores on MMPI-2 scales and cognitive symptom validity test (SVT) failure was investigated in 127 criminal defendants evaluated for competency to stand trial, criminal responsibility, and drug dependence, and 141 personal injury and disability claimants. Results indicated that SVT failure was associated with exaggerated symptom presentation involving somatic complaints i...