The transforming growth factor-beta (TGF-beta) receptor interacting protein TRIP-1 was originally identified as a WD40 repeat-containing protein that has the ability to associate with the TGF-beta type II receptor and is phosphorylated by it (1). However, its function was not known. We now show that TRIP-1 expression represses the ability of TGF-beta to induce transcription from the plasminogen...

In the companion paper to this one (Part I), the Interactions between Soil, Biosphere, andAtmosphere–Total Runoff Integrating Pathways (ISBA-TRIP) continental hydrological system of the Centre National de Recherches Météorologiques is evaluated by using river discharge measurements and terrestrial water storage (TWS) variations derived from three independent datasets of the Gravity Recovery and...

Taxi trajectories reflect human mobility over a road network. Pick-up and drop-off locations in different time periods represent origins and destinations of trips, respectively, demonstrating the spatiotemporal characteristics of human behavior. Each trip can be viewed as a displacement in the random walk model, and the distribution of extracted trips shows a distance decay effect. To identify ...

The main idea of this paper is to represent shopping items through vectors because these vectors act as the base for building embeddings for customers and shopping carts. Also, these vectors are input to the mathematical models that act as either a recommendation engine or help in targeting potential customers. We have used exponential family embeddings as the tool to construct two basic vector...

Understanding the end-to-end packet delay dynamics of the Internet is of crucial importance since it directly affects the QoS (Quality of Services) of various applications, and it enables us to design an efficient congestion control mechanism. In our previous studies, we have measured round-trip time of the Internet, and have modeled its dynamics by the ARX (Auto-Regressive eXogenous) model usi...

We present a constraint programming formulation for the elevator trip origin-destination matrix estimation problem using a lexicographic bi-criteria optimization method where least squares minimization is applied to the measured counts and the minimum information or the maximum entropy approach to the whole matrix. An elevator trip consists of successive stops in one direction of travel with pa...

BACKGROUND Japanese encephalitis virus (JEV) is the major cause of viral encephalitis in Southeast Asia. Vaccination of domestic pigs has been suggested as a "one health" strategy to reduce viral disease transmission to humans. The efficiency of two lentiviral TRIP/JEV vectors expressing the JEV envelope prM and E glycoproteins at eliciting protective humoral response was assessed in a mouse mo...

Public transport systems are vital services in urban environments. The design of these complex socio-technical is continuously evolving to accommodate larger populations, and their adaptation essential supporting the successful sustainable development cities regions. An part this includes working increase passenger safety minimise risk injury. With focus, key objectives current study were ident...

A combined experimental numerical approach is applied to determine the transformation induced plasticity (TRIP)-parameter K for different strength low-alloy steels of grade S355J2+N and S960QL as well as the super martensitic filler CN13-4-IG containing 13 wt% chromium and 4 wt% nickel. The thermo-physical analyses were conducted using a Gleeble (®) 3500 facility. The thermal histories of the s...