Background and objectives: Silymarin is a unique flavonoid complex with documented hepatoprotective properties. Silybum marianum hairy root culture as a source for producing silymarin has been an important strategy for study the cell signaling pathway. In the present investigation Trichoderma strainsSilybum marianum hairy root cultures interactions have been studied. Methods: The effects of two...

this experiment was conducted to evaluate the ability of silybum marianum seeds (sms) on performance, carcass variables, and liver morphology of the broiler chickens contaminated with aflatoxin b1 (afb1). a total of 216 broiler chicks (ross 308) were used. birds were randomly assigned to nine treatment groups, with four replicates and six birds in each replicate. chickens were reared on litter ...

background & aim: increasing of drug resistances and more attention to the hazards of side effects of synthetic drugs has caused extensive researches on medicinal plant resources. the aim of this study was to determination of the chemical composition of native silybum marianum and foeniculum vulgare extractions in ardabil, iran; and investigation of their anticancer effect on liver cancer cell ...

background: this study aims to evaluate the efficacy of silybum marianum seeds (smss) on blood biochemical profile of broiler chickens contaminated with aflatoxin b1 (afb1).  methods: combinations of three levels of afb1 (0, 250 and 500 ppb) with three levels of smss (0, 0.5, and 1.0 %) were incorporated into the basal diet (corn and soybean meal). the effect of nine experimental treatments was...

Milk thistle (Silybum marianum) is a medicinal plant that has been used for thousands of years as a remedy for a variety of ailments. The main component of S. marianum fruit extract (silymarin) is a flavonolignan called silybin, which is not only the major silymarin element but is also the most active ingredient of this extract, which has been confirmed in various studies. This compound belongs...

Use of the herb milk thistle (Silybum marianum) is widespread, and its chemistry has been studied for over 50 years. However, milk thistle endophytes have not been studied previously for their fungal and chemical diversity. We examined the fungal endophytes inhabiting this medicinal herb to determine: (1) species composition and phylogenetic diversity of fungal endophytes; (2) chemical diversit...

milk thistle (silybum marianum (l.) gaertn.) is one of the valuable medicinal plants which used in the treatment of liver disorders. the major active constituents in this plant are flavonolignans, collectively known as silymarin which is a mixture of three isomer silybin, silydianin and silycristin. its therapeutic properties are due to the presence of silymarin. the seeds contain the highest a...