Anthropogenic surface and ground water contamination by chemicals is a global problem, there an urgent need to develop tools identify elucidate biological effects. Contaminants of emerging concern (CECs) are not typically monitored or regulated those with known suspected endocrine disrupting potential have been termed (EDCs). Many CECs be neurotoxic (e.g., insecticides) many incompletely charac...

The ABCB8 is one of the members under ABCB subfamily ATP-Binding Cassette (ABC) transporter which possess ability in regulating intracellular iron and heme transport. loss function mutation gene leads to accumulation cell highly toxic human. However, information regarding expression regulation this remains scarce. Hence, objectives project are determine transcription factors binding site (TFBS)...

Non-methylated islands (NMIs) of DNA are genomic regions that are important for gene regulation and development. A recent study of genome-wide non-methylation data in vertebrates by Long et al. (eLife 2013;2:e00348) has shown that many experimentally identified non-methylated regions do not overlap with classically defined CpG islands which are computationally predicted using simple DNA sequenc...