Ethyl pyruvate (EP) is a simple aliphatic ester derived from pyruvic acid which an endogenous metabolite. Although various studies have investigated the antioxidant and anti-inflammatory properties of EP, there has been only limited research into cytotoxic effect EP on cancer cells. The aim this study was to determine effects cells representing common types. purchased commercially intermediate ...

BmK IT-AP is an excitatory insect-specific beta-toxin with analgesic effect from the Chinese scorpion Buthus martensii Karsch (BmK) and consists of 72 residues cross-linked by four disulfide bridges. The crystal structure of BmK IT-AP has been determined at a resolution of 2.6 A by molecular replacement. Compared with the mammal-selective alpha-toxins consisting of 64 residues from the scorpion...

Although acute myocardial ischemia or infarction may induce the Bezold-Jarisch (BJ) reflex through the activation of serotonin receptors on vagal afferent nerves, the mechanism by which the BJ reflex modulates the dynamic characteristics of arterial pressure (AP) regulation is unknown. The purpose of this study was to examine the effects of the BJ reflex induced by intravenous phenylbiguanide (...

Due to rapid economic development in recent years, China has become a major global source of refractory black carbon (rBC) particles. However, surface rBC measurements have been limited, and the lower troposphere suffers from a complete lack of measurements, especially in heavily rBC-polluted regions such as China’s capital, Beijing (BJ). In this study, we present the first concentration measur...

Inferences from O2 uptake with respect to intramuscular [PCr] kinetics during moderate exercise in humans. J Physiol 518: 921–932, 1999. 20. Rossiter HB, Ward SA, Kowalchuk JM, Howe FA, Griffiths JR, Whipp BJ. Dynamic asymmetry of phosphocreatine concentration and O2 uptake between the onand off-transients of moderateand high-intensity exercise in humans. J Physiol 541: 991–1002, 2002. 21. Siet...

Inferences from O2 uptake with respect to intramuscular [PCr] kinetics during moderate exercise in humans. J Physiol 518: 921–932, 1999. 20. Rossiter HB, Ward SA, Kowalchuk JM, Howe FA, Griffiths JR, Whipp BJ. Dynamic asymmetry of phosphocreatine concentration and O2 uptake between the onand off-transients of moderateand high-intensity exercise in humans. J Physiol 541: 991–1002, 2002. 21. Siet...

Skin aging is caused by the exposure cumulative of ultraviolet radiation, it leads reactive oxygen species (ROS) production in skin. The conditioned medium human Adipose Tissue-derived Mesenchymal Stem Cells (hATMSCs) can scavenge free radicals and increase survival rate skin cells under oxidative stress. This study examined protective effects Conditioned Medium (CM) hATMSCs H2O2-induced fibrob...