Blazar spectral energy distributions (SEDs) are double peaked and follow a selfsimilar sequence in luminosity. The so-called “blue” blazars, whose first SED component peaks at X-ray energies, are TeV sources, although with a relatively small fraction of their bolometric luminosities. The “red” blazars, with SED peaks in the infrared-optical range, appear to emit relatively more power in the gam...

The present study evaluated the impact of moderate exercise training on the cardiac tolerance to acute pressure overload. Male Wistar rats were randomly submitted to exercise training or sedentary lifestyle for 14 wk. At the end of this period, the animals were anaesthetized, mechanically ventilated, and submitted to hemodynamic evaluation with biventricular tip pressure manometers. Acute press...

The protoplanetary discs of T Tauri and Herbig Ae/Be stars have been studied by using geometric disc models to fit their spectral energy distribution (SED). The simulations provide means to reproduce the signatures of different circumstellar structures, which are related to different levels of infrared excess. Aiming to improve our previous model that assumed a simple flat disc configuration, i...

OBJECTIVE We employ a nasal tip finite element model (FEM) to evaluate contributions of two of the three major tip support mechanisms: attachments between the upper and lower lateral cartilages and attachment of the medial crura to the caudal septum. STUDY DESIGN The nasal tip FEM computed stress distribution and strain energy density (SED) during nasal tip compression. We examined the impact...

We calculate the spectral energy distribution (SED) of electromagnetic radiation and the spectrum of high energy neutrinos from BL Lac objects in the context of the Synchrotron Proton Blazar Model. In this model, the high energy hump of the SED is due to accelerated protons, while most of the low energy hump is due to synchrotron radiation by co-accelerated electrons. To accelerate protons to s...

PURPOSE This study investigated the effects of ovariectomy (Ovx) and 12 weeks of resistance training (RT) on gene expression of GLUT2, the main glucose transporter in the liver, and on PPARγ, a transcription factor known to target GLUT2 expression. METHODS Forty Holtzman rats were divided into 5 groups: Sham-sedentary (Sed), Sham- RT, Ovx-Sed, Ovx-RT, and Ovx-Sed with hormone replacement (E2)...

Lifelong exercise is associated with regulation of skeletal mass and function, reductions in frailty, and successful aging. Yet, the influence of exercise on myostatin and myostatin-interacting factors is relatively under examined in older males. Therefore, we investigated whether serum total myostatin, free myostatin, follistatin, and growth and differentiation factor 11 (GDF11) were altered f...

BACKGROUND Spondyloepiphyseal dysplasia (SED) is a rare disease that causes vertebral abnormalities and short-trunk dwarfism. The two forms of SED are congenita and tarda. Each form arises in a genetically distinct fashion and manifests with a different set of complications. SED congenita is more severe, and patients usually display atlantoaxial instability and odontoid hypoplasia. Patients oft...

UNLABELLED Getting enough sleep, exercising, and limiting sedentary activities can greatly contribute to disease prevention and overall health and longevity. Measuring the full 24-h activity cycle-sleep, sedentary behavior (SED), light-intensity physical activity (LPA), and moderate-to-vigorous physical activity (MVPA)-may now be feasible using small wearable devices. PURPOSE This study compa...

Objective. We evaluated the influence of exercise on functional capacity, cardiac remodeling, and skeletal muscle oxidative stress, MAPK, and NF-κB pathway in rats with aortic stenosis- (AS-) induced heart failure (HF). Methods and Results. Eighteen weeks after AS induction, rats were assigned into sedentary control (C-Sed), exercised control (C-Ex), sedentary AS (AS-Sed), and exercised AS (AS-...