Mucous membrane pemphigoid (MMP) is an autoimmune blistering disease that most frequently affects the oral cavity and conjunctivae. Additional skin lesions may appear in about a quarter of patients. The current therapeutic armamentarium mainly based on long-term immunosuppression, which associated with high number adverse events not effective. Here, we investigated effects topical conjunctival ...

NB, being a highly metastatic cancer, is one of the leading causes cancer-related deaths in children. Increased disease recurrence and clinical resistance patients with high-risk NBs (HR-NBs) result poor outcomes lower overall survival. However, paucity appropriate vivo models for HR-NB metastasis has limited investigations into underlying biology metastasis. This study was designed to address ...

Postmenopausal women represent a vulnerable population towards endocrine disruptors due to hormonal deficit. We previously demonstrated that chronic exposure of ovariectomized C57Bl6/J mice fed high-fat, high-sucrose diet low-dose mixture chemicals with one dioxin, polychlorobiphenyl, phthalate, and bisphenol A triggered metabolic alterations in the liver but intestine was not explored. Yet, ga...