Schistosomiasis is a parasitic disease caused by the schistosoma worm. A snail can act as intermediate host for parasite. Snail-population control considered to be an effective way schistosomiasis spread. In this paper, we discuss model incorporating predator biological agent. We prove that solutions of are non-negative and bounded. The existence condition equilibrium points investigated. deter...

BACKGROUND The preferential use of aerobic glycolysis by tumor cells lead to high accumulation of lactate in tumor microenvironment. Clinical evidence has linked elevated lactate concentration with cancer outcomes. However, the role and molecular mechanisms of lactate in cellular senescence and tumor progression remain elusive. METHODS The function of Snail in lactate-induced EMT in lung canc...

—The faucet snail Bithynia tentaculata, a nonindigenous aquatic snail from Eurasia, was introduced into Lake Michigan in 1871 and has spread to the mid-Atlantic states, the Great Lakes region, Montana, and most recently, the Mississippi River. The faucet snail serves as intermediate host for several trematodes that have caused large-scale mortality among water birds, primarily in the Great Lake...

The mortality caused to the snail Bulinus wrighti (The snail vector of urinary schistosomiasis) by different extracts of two species of plants belonging to the family Euphorbiaceae has been investigated. It was found that very low concentrations of fresh leaf extracts were effective in killing the snail. The LC50 of methanol and acetone extracts for Euphorbia schimperiana and Euphorbia heliosco...

Uric acid accumulates in several tissues of the Indian apple snail, P. globosa, during aestivation. This accumulation is particularly high in the foot muscle and reproductive organs. Since the kidney, a tiny organ in the snail, has only a limited capacity to store uric acid, extrarenal tissues are used as storage depots of uric acid during aestivation. It is suggested that the aestivating snail...

The suitability of date-seed/snail shells as a carburizer for enhanced mechanical properties mild-steel using the packed carburization technique was investigated in this work. Standard tensile, impact and hardness test samples prepared from were subjected to pack-carburization process mixtures date-seed snail shell ratio 60:40 respectively at 800, 900, 1 000 °C 3 hours. carburized quenched wate...

Transcriptional repressor Snail is a master regulator of epithelial–mesenchymal transition (EMT), yet the epigenetic mechanism governing Snail to induce EMT is not well understood. Here, we report that in pancreatic ductal adenocarcinoma (PDAC), elevated levels of the ubiquitin E3 ligase Ring1B and Snail, along with elevated monoubiquitination of H2A at K119 (H2AK119Ub1), are highly correlated ...

Intertidal snail-trematode communities in southern Thailand were examined before and after the South Asia tsunami. Infection rates and species diversity of cercaria in the host snail Cerithidea in tidal zones did not change significantly from one year before to one month after the tsunami. However, the host snails C. quadrata, C. alata and C. obtusa disappeared from greatly damaged sites. It is...

Delaminated neuroblasts in Drosophila function as stem cells during embryonic central nervous system development. They go through repeated asymmetric divisions to generate multiple ganglion mother cells, which divide only once more to produce postmitotic neurons. Snail, a zinc-finger transcriptional repressor, is a pan-neural protein, based on its extensive expression in neuroblasts. Previous r...

BACKGROUND AND OBJECTIVE Epithelial-mesenchymal transition (EMT) is considered to be one of the major molecular mechanisms inducing tumor invasion and metastasis. The loss of epithelial cell polarity is a hallmark of the EMT process. Epithelial markers such as Claudin are lost in EMT. Snail is a major transcription factor governing EMT. Recent studies about the mechanism of tumor invasion and m...