INTRODUCTION Cognitive tests and nonamyloid imaging biomarkers do not consistently identify preclinical AD. The objective of this study was to evaluate whether white matter hyperintensity (WMH) volume, a cerebrovascular disease marker, is more associated with preclinical AD than conventional AD biomarkers and cognitive tests. METHODS Elderly controls enrolled in the Alzheimer's Disease Neuroi...

We have measured the absolute optical frequency of the cesium D1 line at 335 THz (895 nm). This frequency provides an important link for a new determination of the fine structure constant a. The D1 line has been compared with the fourth harmonic of a methane stabilized He-Ne laser at 88.4 THz (3.39 mm). To measure the frequency mismatch of 18.39 THz between 4 3 88.4 THz ­ 354 THz and the D1 lin...

OBJECTIVE To evaluate the role of WF10-immunotherapy in reducing oro-pharyngeal complications in head and neck cancer chemoradiotherapy. MATERIAL AND METHOD Thirteen patients were enrolled and assigned either to WF10- (n = 6) or control group (n = 7). After completion of their initial (neoadjuvant) chemotherapy, patients received WF10 intravenous infusions at 0.5 mL/kg body weight/day for fiv...

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We present new results of a survey for weak magnetic fields among DA white dwarfs with inclusion of some brighter hot subdwarf stars. We have detected variable circular polarization in the Hα line of the hot subdwarf star Feige 34 (SP: sdO). From these data, we estimate that the longitudinal magnetic field of this star varies from −1.1 ± 3.2 kG to +9.6 ± 2.6 kG, with a mean of about +5 kG and a...

BACKGROUND We earlier observed altered expression of p53 and Bcl-xL in oral cancer cell lines/tissues and wanted to evaluate these proteins for prediction of radiotherapy response and outcome. METHODS Thirty-nine paraffin-embedded, pretreatment oral cancer biopsies were analyzed for protein expression using immunohistochemistry and correlated with tumor response to radiotherapy and disease-fr...

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Potassium turnover was studied in rainbow trout, Salmo gairdneri Richardson, adapted to fresh water or 22 %o sea water using K and Rb. Potassium space of the whole body increased with time and was about 5 mmol kg" after 20h, while Rb space under the same conditions was only about 0-5 mmol kg", indicating slow penetration of body K by Rb + , especially in muscle and red blood cells. Potassium in...

The chemokine RANTES (regulated on activation, normal T cell expressed and secreted) is a potent regulator of leukocyte trafficking. RANTES preferentially attracts mature CD4 cells as well as macrophages and eosinophils, but not neutrophils. In total, 128 children with meningococcal disease were prospectively studied, and the role of RANTES in the pathophysiology of meningococcal disease was as...

Manipulations have been considered effective only in the early postoperative period. From a total joint registry containing 9640 primary total knee arthroplasties (TKAs), 195 patients who underwent manipulation under anesthesia (MUA) were identified. A total of 102 had MUA within 90 days (early), and 93 more than 90 days (late) after TKA. Average pain (10-point scale), satisfaction (10-point sc...