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Background: Circulating cell-free DNA (cfDNA) is a novel type of biomarker with broad utility in diagnostic medicine, based on the release fragments from dying cells to circulation. We developed an approach for identifying tissue origins cfDNA, using cell-type-specific methylation patterns, massive reference atlas genome-wide methylomes multiple human tissues and cell types. Cancer inflicts dam...

ABSTRACT This work is devoted to the study of broad-band 0.8–79 keV spectral and timing properties poorly studied X-ray pulsar XTE J1859+083 during its 2015 outburst based on data from NuSTAR Swift observatories. We show that source pulse profile has complex shape depends energy band. Pulse fraction constant value around 35 per cent in broad band, this behaviour atypical for pulsars. At same ti...

Adhesively bonded structures are potentially lighter in weight than mechanically fastened ones, but existing surface treatments are often considered unreliable. Two main problems in achieving reproducible and durable adhesive bonds are surface contamination and variability in standard surface preparation techniques. In this work three surface pretreatments were compared: laser etching with and ...

R. Arinero, C. Riedel, G. A. Schwartz, G. Lévêque, A. Alegría, Ph. Tordjeman, N. E. Israeloff, M. Ramonda and J. Colmenero 1 IES, UMR CNRS 5214, Université Montpellier II, CC 083, Place E. Bataillon, 34095 Montpellier Cedex, France 2 Donostia International Physics Center (DIPC), Paseo Manuel de Lardizábal 4, 20018 San Sebastián, Spain. 3 Departamento de Física de Materiales UPV/EHU, Facultad de...

As part of the ANDRILL McMurdo Ice Shelf (MIS) Project two comprehensive sets of geophysical data were collected on ice at the AND-1B drillsite. Whole-core physical properties were determined with high vertical resolution to a depth of 1285 mbsf. A multi-sensor-core-logger was used to determine bulk density, sonic velocity, magnetic susceptibility and electrical resistivity. After drilling, a s...