Alzheimer's disease is considered the most common cause of dementia. At present, no definite cure is available for healing the disorders and stopping the disease progress. The aim of this study is to study the effects of piracetam, rivastigmine and their joint consumption on MMSE score status in patients with Alzheimer disease. This interventional study was carried out on 64 patients with ...

BACKGROUND AND PURPOSE 3β-Hydroxysteroid-Δ24 reductase (DHCR24) or selective alzheimer disease indicator 1 (seladin-1), an enzyme of cholesterol biosynthetic pathway, has been implicated in neuroprotection, oxidative stress, and inflammation. However, its role in ischemic stroke remains unexplored. The aim of this study was to characterize the effect of seladin-1/DHCR24 using an experimental st...

.......................................................................................page 10 Chapter One: Evidence for a Role of Luteinizing Hormone in Alzheimer Disease Abstract...............................................................................page 13 Background...........................................................................page 14 Gender Differences in Alzheimer Disea...

OBJECTIVES To measure the rate and predictors of change on the Mini-Mental State Examination in patients with Parkinson disease (PD) and to compare that change with the Mini-Mental State Examination changes of patients with Alzheimer disease and nondemented subjects. PATIENTS Patients with PD were drawn from a community-based cohort in Rogaland County, Norway. Those who were without cognitive...

L aser capture microdissection (LCM) is a new technology that is becoming increasingly important for studies of neurodegenerative disorders. A characteristic feature of all neurodegenerative diseases is “selective vulnerability.” In each of the disorders, there is selective degeneration of particular types of neurons, with relative preservation of much of the rest of the brain. Familiar example...

#### Notable in Neurology This Week issue features an article that analyzes the trends epilepsy center services United States; another evaluates association between metabolomic profiles and incident stroke. A featured Review examines burden of pulmonary arteriovenous malformations on ischemic ### Association Neurofibrillary Tangle Distribution With Age at Onset–Related Clinical Heterogeneity Al...

BACKGROUND AND PURPOSE The hippocampal fissure is a fetal sulcus that, except for its most medial part (the superficial hippocampal sulcus), is normally obliterated. Hippocampal cavities are residual cysts attributable to lack of hippocampal fissure obliteration. We hypothesized that either hippocampal sulcus enlargement or an increase in number or size of hippocampal cavities could be associat...