BACKGROUND AND AIM Maximal mouth opening (MMO) is used as a marker of masticatory pathology. However, MMO among children varies considerably with their age, height, sex, and race. While accurate percentile of normal mouth opening and relationship with anthropometric measurement are not precisely defined for the Indian population, we designed prospective, observational study to define the percen...

BACKGROUND Little is known about motor function in mild cognitive impairment (MCI) and its relation to the risk of Alzheimer disease (AD). OBJECTIVE To examine motor function in persons with MCI and its relation to risk of AD. DESIGN Longitudinal cohort study. SETTING More than 40 Catholic religious orders across the United States. PARTICIPANTS We studied 816 older Catholic clergy membe...

Abstract Expert judgments on solar geoengineering (SG) inform policy decisions and influence public opinions. We performed face-to-face interviews using formal expert elicitation methods with 13 US Chinese climate experts randomly selected from IPCC authors or supplemented by snowball sampling. compare their change, SG research, governance, deployment. In contrast to existing literature that of...

Radiation management (RM) has been proposed as a conceivable climate engineering (CE) intervention to mitigate global warming. In this study, we used coupled model (MPI-ESM) with very idealized setup investigate the efficacy and risks of CE at local scale in space time (regional radiation management, RRM) assuming that cloud modification is technically possible. RM implemented by brightening lo...

The effects of keyswitch stiffness and key action on typing force, electromyography (EMG), and subjective preference were examined. Each subject's own keyboard (with an audible key click and key activation force of 0.72 N) and three keyboards with no key click that were identical in design but had different key activation forces (0.28 N, 0.56 N, and 0.83 N) were used. Subjects (24 female transc...

OBJECTIVE To differentiate prostate cancer lesions in transition zone by diffusion-weighted-MRI (DW-MRI). METHODS Data from a total of 63 patients who underwent preoperative DWI (b of 0-1000 s/mm2) were prospectively collected and processed by a monoexponential (DWI) model and compared with a biexponential (IVIM) model for quantitation of apparent diffusion coefficients (ADCs), perfusion frac...

BACKGROUND An hCG regression curve has been used to predict the natural history and response to chemotherapy in gestational trophoblastic disease. We constructed hCG regression curves in high-risk gestational trophoblastic neoplasia (GTN) treated with EMA/CO and identified an optimal hCG level to detect EMA/CO resistance in GTN. MATERIALS AND METHODS Eighty-one women with GTN treated with EMA...

OBJECTIVE To investigate whether changing levels of exercise during pregnancy are related to altered neonatal adiposity. DESIGN Secondary analysis of data from a prospective cohort study. SETTING Cork, Ireland. PARTICIPANTS 1200 mother - infant pairs recruited as part of a prospective birth cohort, Babies After SCOPE: Evaluating the Longitudinal Impact Using Neurological and Nutritional E...

BACKGROUND Dyslipidemias are the major cause for atherosclerosis. They may act synergistically with nonlipid risk factors to increase atherogenesis. In the present study, we examined the effects of dyslipidemias from childhood to adulthood and their interaction with nonlipid risk factors on markers of subclinical atherosclerosis. METHODS AND RESULTS Study subjects were participants of the lon...

INTRODUCTION Elevated levels of chemokines have been reported in plasma and brain tissue of individuals with Autism Spectrum Disorders (ASD). The aim of this study was to examine chemokine levels in amniotic fluid (AF) samples of individuals diagnosed with ASD and their controls. MATERIAL AND METHODS A Danish Historic Birth Cohort (HBC) kept at Statens Serum Institute, Copenhagen was utilized...