نتایج جستجو برای: 114

تعداد نتایج: 17283  

2007
Xuejun Zhang Gobert Lee Tetsuji Tajima Teruhiko Kitagawa Masayuki Kanematsu Xiangrong Zhou Takeshi Hara Hiroshi Fujita Hiroshi Kondo Hiroaki Hoshi Shigeru Nawano Kenji Shinozaki

Segmentation of an abnormal liver region based on CT or MR images is a crucial step in surgical planning. However, precisely carrying out this step remains a challenge due to either connectivities of the liver to other organs or the shape, internal texture, and homogeneity of liver that maybe extensively affected in case of liver diseases. Here, we propose a non-density based method for extract...

Journal: :Clinical genetics 2006
A Trott L B Jardim H T Ludwig J A M Saute O Artigalás C Kieling H Y C Wanderley C R M Rieder T L Monte M Socal I Alonso A Ferro T Carvalho M do Céu Moreira P Mendonça F Ferreirinha I Silveira J Sequeiros R Giugliani M L Saraiva-Pereira

To the Editor: Dominant spinocerebellar ataxias (SCAs) are a group of neurodegenerative diseases that affect the cerebellum, brain stem, and spinocerebellar tracts. SCA1, SCA2, SCA3, SCA6, SCA7, SCA12, SCA17 and dentatorubral pallidoluysian atrophy (DRPLA) are caused by CAG trinucleotide repeat expansions (1). SCA8 has a CTG expansion in the causative gene. SCA10 has been found to represent a l...

Journal: :European journal of endocrinology 2003
Thomas Meissner Udo Wendel Peter Burgard Silvia Schaetzle Ertan Mayatepek

BACKGROUND The term congenital hyperinsulinism (CHI) comprises a group of different genetic disorders with the common finding of recurrent episodes of hyperinsulinemic hypoglycemia. OBJECTIVE To evaluate the clinical presentation, diagnostic criteria, treatment and long-term follow-up in a large cohort of CHI patients. PATIENTS The data from 114 patients from different hospitals were obtain...

2017
Yujie Zhao Junshan Wang Zhanju Liu Hui Lin Yanhong Shi Xiaomin Sun

This study aimed to investigate the pulmonary function in patients with inflammatory bowel disease (IBD) and its clinical feature and risk factors.One hundred fourteen patients with IBD and 120 healthy subjects were recruited. The medical information including general situation, biochemical examinations, lung function, and the treatment was recorded and analyzed.In 107 patients (107/114, 93.86%...

Journal: :Auris, nasus, larynx 1983
C H Raine S D Singh

OBJECTIVES There is a marked diversity in the reported success rates for achieving an intact tympanic membrane following tympanoplasty. Controversy exists about the factors thought to influence surgical outcome. These facts have important implications for the selection of patients who would benefit the most. This study reviews the factors thought to determine the anatomical and functional succe...

2012
Jia-Wang Wang Kunyu Li Richard F. Lockey Subhra Mohapatra Shyam Mohapatra

helminthic infections, and allergy. They are closely associated with recruiting and amplifying T helper 2 (Th2) lymphocyte response in contrast to Th1asscoiated CAMs. Wide donor-to-donor variability of human primary monocytes and their limited life span in vitro is a current impediment to investigating human AAM biology and their contribution to enhancing Th2mediated pathologic inflammation fou...

1998
Edward P. Tagge André Hebra Aron Goldberg Kathryn Jacques Sherron Jackson H. Biemann Othersen C.K. Yeung K.H. Lee W.T. Ng Y.H. Tam K.F. Yip Edward Tagge Jennifer Walker Elise Hardee Mary Ann Hopkins Gustavo Stringel Harsh Grewal Samuel D. Smith Richard J. Jackson Lester Permuth Maribel de Hoyos Yaritza Perez Lugo Vicente Julio Teixeira

Objectives: Since pediatric cholelithiasis is uncommon, to date there have not been any large series reporting the results of laparoscopic cholecystectomy performed in children. However, at our institution, the combination of an early commitment to laparoscopic techniques for children and access to a large population of pediatric patients with sickle cell disease have provided a significant exp...

2014
Shun-Chung Yang Der-Chuen Lee Tung-Yuan Ho Liang-Saw Wen Hsu-Han Yang

*Correspondence: Der-Chuen Lee, Institute of Earth Sciences, Academia Sinica, 128, Sec. 2, Academia Rd., Nankang, Taipei 115, Taiwan e-mail: [email protected] The dissolved concentration and isotopic compositions of cadmium (Cd) in the seawater of the West Philippine Sea (WPS) were determined. In general, Cd isotopic composition in the water column decreased with depth, with 114/110 11 ...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 1999
T C McMorris A N Elayadi J Yu Y Hu M J Kelner

Acylfulvenes are a potent class of antitumor agents derived from illudin S, a fungal sesquiterpene. Illudin S possesses antitumor activity but has a poor therapeutic index. Acylfulvene is 100-fold less toxic against human lung adenocarcinoma cells than illudin S, but inhibits tumor growth in human xenografts, opposite to illudin S. An analog of acylfulvene, MGI 114 (hydroxymethylacylfulvene), s...

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