through the formation of early products such as Schiff base and Amadori rearrangement products, to the formation of advanced glycation endproducts (AGEs). Ne-(Carboxymethyl)lysine (CML), a major structure in AGEs, is accumulated in several tissues of human and animal during aging and various disease states including age-related macular degeneration (AMD). Choroidal neovascularization leads the ...

This paper explores what high-performing firms specifically do to gain the greatest benefits from their IT investments. It identifies several IT-specific factors such as Data/Process Standardization, Systems Integration and Application Integration as practices that are correlated with significant IT impact on a key business performance metric: customer satisfaction. The firms interviewed in thi...

ACKNOWLEDGEMENT This monograph is based on the papers from a technical review on " Imaging Techniques in Medications Development: Preclinical and Clinical Aspects " held in 1992. The review meeting was sponsored by the National Institute on Drug Abuse. The National Institute on Drug Abuse has obtained permission from the copyright holders to reproduce certain previously published material as no...

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The presence of pathogenic Shiga toxin–producing Escherichia coli (STEC) in dairy products represents a public health concern because its ability to produce the toxins Stx1 and Stx2, which cause intestinal diseases. Monitoring stages milk production checking for contamination are crucial steps ensure safety. This study aimed report occurrence thermotolerant coliforms, E. coli, STEC strains past...

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BACKGROUND Treatments that target cancer stem cells play an important role in the controlling and eliminating of tumor initiation as well as in development, progression, and chemotherapy/radiotherapy resistance. In our previous study, we cultured and harvested human laryngeal cancer stem cells (CSCs) and applied microRNA biochips to screen differentially expressed miRNAs that were related to ra...

Although ancient Greek physicians described several mental disorders, their medical texts bring little information about postpartum depression as defined by modern medicine. Only one reference in ancient Greek medical literature - a passage from Soranus' Gynaeciorum libri IV - can be considered a clear presentation of this mental disorder. Soranus' interpretation seems to be firmly based on the...