1 year and are subjected to similar analyses. If disease progression is unique to mice in our facility, it might suggest that environmental or infectious agents can play a role in the progression to the more severe phenotype in a subset of mice in the context of 12/15lipoxygenase deficiency. It is important to stress, however, that the defects we reported in the majority of Alox15 mice that are...

Source and Description of Primers. The initial primers for the PCR were designed based on human DNA sequence (accession no. X92412; Kolmerer et al., 1996). The position of the forward and reverse primers corresponded to exon 3 and exon 5, respectively. These primers are expected to amplify a fragment of 1.93 kb from human DNA. A PCR fragment of 2.1 kb was amplified from porcine genomic DNA. Par...

Published papers rarely disclose implementation details. In this paper we show how such details can account for speedups of up to a factor of 28 for different implementations of the same algorithm. We perform an in-depth analysis of the most popular benchmark in heuristic search: the 15-puzzle. We study implementation choices in C++ for both IDA* and A* using the Manhattan distance heuristic. R...

This is a chapter from the book System Design, Modeling, and Simulation using Ptolemy II This work is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License. To view a copy of this license, visit: http://creativecommons.org/licenses/by-sa/3.0/, or send a letter to Creative Commons, 444 Castro Street, Suite 900, Mountain View, California, 94041, USA. Permissions beyond t...

SBA-15 is an interesting mesoporous silica material having highly ordered nanopores and a large surface area, which is widely employed as catalyst supports, absorbents, drug delivery materials, etc. Since it has a lack of functionality, heteroatoms and organic functional groups have been incorporated by direct or post-synthesis methods in order to modify their functionality. The aim of this art...

Current models of T cell memory implicate a critical role for IL-7 in the effector-to-memory transition, raising the possibility that IL-7 therapy might enhance vaccine responses. IL-7 has not been studied, to our knowledge, before now for adjuvant activity. We administered recombinant human IL-7 (rhIL-7) to mice during immunization against the male antigen HY and compared these results with th...