Differentiated CD4(+) T cells preserve plasticity under various conditions. However, the stability of Th1 cells is unclear, as is whether Th1 cells can convert into Th17 cells and thereby contribute to the generation of IFN-γ(+) IL-17(+) CD4(+) T cells, the number of which correlates with severity of colitis. We investigated whether IFN-γ(+) Th1 cells can convert into Th17 cells under intestina...

This study was designed to analyze the relationship between serum creatinine and body mass index in children in Xinjiang, China. We used a stratified sampling method to select 5222 children aged 6-17 years in 3 areas in Xinjiang and then measured serum creatinine with an enzymatic method. Our analysis showed that the mean serum creatinine of the various age groups differed, and the reference va...

Active components of complementary/alternative medicines and natural supplements are often anionic compounds and flavonoids. As such, organic anion transporters (OATs) may play a key role in their pharmacokinetic and pharmacological profiles, and represent sites for adverse drug-drug interactions. Therefore, we assessed the inhibitory effects of nine natural products, including flavonoids (cate...

Synthesis of two ent-kaurane diterpene glycosides, steviol 19-O-β-D-glucopyranosiduronic acid (steviol glucuronide, 5), and 13-hydroxy ent-kaur-16-en-19-oic acid-β-D-glucopyranosyl ester (7) has been achieved from a common starting material, steviol, using phase transfer catalyst. Also, synthesis of an additional 17-nor-ent-kaurane glycoside, namely 13-methyl-16-oxo-17-nor-ent-kauran-19-oic aci...

RORγt(+) T(H)17 cells are a proinflammatory CD4(+) T-cell population associated with autoimmune tissue injury. In mice, priming of T(H)17 requires TGF-β, which alone directs the priming of FOXP3(+) regulatory T cells (Treg), in association with inflammatory cytokines. Priming of human T(H)17 cells from conventional naive CD4(+) T cells under similar conditions, however, has proved difficult to ...

In [17] the author and A. Vershik have shown that for β = 1 2 (1 + √ 5) and the alphabet {0, 1} the infinite Bernoulli convolution (= the Erdös measure) has a property similar to the Lebesgue measure. Namely, it is quasi-invariant of type II1 under the β-shift, and the natural extension of the β-shift provided with the measure equivalent to the Erdös measure, is Bernoulli. In this note we exten...

Abstract C 23 H 17 N 3 O 5 Cu, monoclinic, P 2 1 / n (no. 14), a = 11.49510(10) Å, b 8.69660(10) c 21.1454(2) β 105.433(1)°, V 2037.65(4) Å , Z 4, R gt ( F ) 0.0298, w ref 0.0862, T 294 K.

Abstract C 47 H 37 Fe 2 NO 4 P Se , monoclinic, 1 / n (no. 14), a = 12.8144(11) Å, b 17.9714(15) c 19.1077(17) β 104.329(4)°, V 4263.5(6) Å 3 Z 4, R gt ( F ) 0.0420, w ref 0.0968, T 298(2) K.

Abstract C 17 H 13 ClF 4 O 3 S, monoclinic, P 21 / n (no. 14), a = 17.0097(10) Å, b 4.4625(3) c 22.9520(19) β 102.933(7)°, V 11698.0(2) Å , Z 4, R gt ( F ) 0.0606, wR ref 2 0.1605, T 120 K.