We report here on a rare case of primary AL hepatic amyloidosis associated with multiple myeloma in a 64-year-old woman. The patient was referred for evaluating her progressive jaundice and right upper quadrant pain. (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET)/computed tomography (CT) showed diffusely and markedly increased (18)F-FDG uptake in the liver. Although the...

BACKGROUND Cardiac sarcoidosis (CS) is a potentially fatal condition lacking a single test with acceptable diagnostic accuracy. (18)F-FDG PET/CT has emerged as a promising imaging modality, but is challenged by physiological myocardial glucose uptake. An alternative tracer, (68)Ga-DOTANOC, binds to somatostatin receptors on inflammatory cells in sarcoid granulomas. We therefore aimed to conduct...

background: to retrospectively describe imaging characteristics of liver metastases on fused fdg-pet/ mri data sets and to compare the diagnostic accuracy of mri and fused fdg-pet/mri data sets for the detection of liver metastases in patients undergoing systemic anticancer treatment. materials and methods: 43 oncological patients (mean age: 56+/- 11 years) were investigated by fdg-pet/ct and l...

UNLABELLED The aim of this study was to investigate the relationship between the tumor uptake of 16α-(18)F-fluoro-17β-estradiol ((18)F-FES) and (18)F-FDG using PET and expressions of sex hormone receptors, such as estrogen receptor (ER), as well as glucose transporter 1 (GLUT-1) and Ki-67 analyzed by the immunohistochemistry method in mesenchymal uterine tumors. METHODS Forty-seven patients w...

UNLABELLED The aim of this study was to compare the grading and prognostic value of l-[methyl-(11)C]-methionine ((11)C-MET) PET in glioma patients with (18)F-FDG PET and contrast-enhanced MRI. METHODS Patients (n = 102) with histopathologically confirmed gliomas were followed up for an average of 34.6 ± 3.8 mo after PET. The median survival was 18 ± 4.7 mo in the high-grade glioma group and 5...

UNLABELLED We evaluated the amino acid and glucose metabolism of brain tumors by using PET with 3,4-dihydroxy-6-(18)F-fluoro-l-phenylalanine ((18)F-FDOPA) and (18)F-FDG. METHODS Eighty-one patients undergoing evaluation for brain tumors were studied. Initially, 30 patients underwent PET with (18)F-FDOPA and (18)F-FDG within the same week. Tracer kinetics in normal brain and tumor tissues were...

The accuracy of mediastinal staging is of paramount importance in the management of patients with non-small cell lung cancer (NSCLC) to select only those patients who might benefit from upfront resection or multimodality treatment. Although CT is the imaging technique of first choice, its performance characteristics have led to an increased use of both EUS-FNA and (18)FDG-PET to improve (medias...

BACKGROUND The purpose of this prospective study was to identify if F-18-fluorodeoxy-D-glucose positron emission tomography (F-18-FDG PET) was a reliable noninvasive surrogate of histologic response in determining the efficacy of neoadjuvant chemotherapy before surgical resection in primary osteosarcoma. METHODS Between January 2003 and December 2003, 10 patients with primary osteosarcomas we...

UNLABELLED New imaging techniques have been introduced to assess the extent and severity of disease in multiple myeloma (MM) patients. The aim of our study was to compare newer imaging modalities-such as (18)F-FDG PET/CT, (99m)Tc-methoxyisobutylisonitrile ((99m)Tc-MIBI) scintigraphy, and MRI-to assess their relative contribution in the evaluation of MM patients at diagnosis. METHODS Thirty-th...

Background: The role of fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) in the surgical approach solitary pulmonary nodule (SPN) is still debated, as increased metabolic avidity lesion was not a sure sign malignancy. purpose this study to evaluate effectiveness 18F-FDG-PET/CT characterization SPN based on analysis most recent data literature.