INTRODUCTION Higher and lower-middle income countries are increasingly affected by obesity. Obesity-related diseases are placing a substantial health and economic burden on Brazil. Our aim is to measure the future consequences of these trends on the associated disease burden and health care costs. METHOD A previously developed micro-simulation model is used to project the extent of obesity, o...

This paper discusses some of the recent cooperative multiagent systems work in the TEAMCORE lab at the University of Southern California. Based in part on an invited talk at the CARE 2010 workshop, we highlight how and why execution-time reasoning has been supplementing, or replacing, planning-time reasoning in such systems.

The evaluation of climatic change impact on maize grain and biomass yield under different N management practices through a well-calibrated validated APSIM model in Vertisol central India has been made. Climate scenarios were derived from seven global climate models (GCM) for two representative concentration pathways (RCPs), i.e. RCP4.5 RCP8.5, two-time slices, 2050 2080. five scenarios, namely ...

The rise in the frequency and magnitude of extreme temperature phenomena across globe has led to recurrent incidence global climate hazards, which have had severe effects on socioeconomic development. daily maximum minimum datasets 27 sites Bangladesh were used detect spatiotemporal trends extremes over during 1980–2017 based ten indices using multi-statistical modeling namely linear regression...

With AD, 36 million individuals are estimated to be affected in 2010 growing to 115 million by 2050 [2]. And AD caregivers in a 2 to 1 ratio add an additional 200 million or so individuals indirectly affected by the disease. These are staggering numbers by any measure — but especially for two diseases with few, if any, effective treatments despite major investments by biopharma over the past tw...

Exosomes are extracellular membrane vesicles whose biogenesis by exocytosis of multivesicular endosomes was discovered in 1983. Since their discovery 30 years ago, it has become clear that exosomes contribute to many aspects of physiology and disease, including intercellular communication. We discuss the initial experiments that led to the discovery of exosomes and highlight some of the excitin...

Population distribution estimates by age and race/ethnicity from the U.S. Census Bureau for the years 2010 and 2050 were combined with estimates of stroke incidence from population-based surveillance studies to forecast the distribution of incident stroke cases for the years 2010 and 2050. Over these 40 years, the number of incident strokes will more than double, with the majority of the increa...

Current world population is expected to reach 10.5 billion by 2050 (UN March, 2013), further adding to global food security concerns. This increase translates into 33% more human mouths to feed, with the greatest demand growth in the poor communities of the world. According to Alexandratos and Bruinsma (2012), food supplies would need to increase by 60% (estimated at 2005 food production levels...