نتایج جستجو برای: 199 nacu3btc2
تعداد نتایج: 9203 فیلتر نتایج به سال:
The aim of the study was to determine the optimum concentration of the mare serum (MS) for sheep in vitro oocyte maturation. Sheep ovaries were collected from a local abattoir and transported within 1 h to the laboratory in a warm saline solution (30 – 35C), supplemented with 100 IU penicillin G and 100 g streptomycin sulfate/ml. Cumulus-oocyte complexes (COC’s) were obtained by slicing of foll...
OBJECTIVE Many patients with irritable bowel syndrome IBS not only have abdominal pain but also may suffer from visceral hypersensitivity and heighted visceral nociception. Moreover, IBS has few effective therapeutic agents and mechanisms of disease are unclear. Our goals were to (i) identify microRNA (miRNA) expression, signalling and targets in human colon (controls; patients with IBS); (ii) ...
PURPOSE To investigate the roles of BCL2, MCL1, and BCL-XL in the survival of diffuse large B-cell lymphoma (DLBCL). EXPERIMENTAL DESIGNS Immunohistochemical analysis of 105 primary DLBCL samples, and Western blot analysis of 18 DLBCL cell lines for the expression of BCL2, MCL1, and BCL-XL. Pharmacologic targeting of BCL2, MCL1, and BCL-XL with ABT-199, homoharringtonine (HHT), and ABT-737. A...
Impact of low-level viremia on clinical and virological outcomes in treated HIV-1-infected patients.
BACKGROUND The goal of antiretroviral therapy (ART) is to reduce HIV-related morbidity and mortality by suppressing HIV replication. The prognostic value of persistent low-level viremia (LLV), particularly for clinical outcomes, is unknown. OBJECTIVE Assess the association of different levels of LLV with virological failure, AIDS event, and death among HIV-infected patients receiving combinat...
Reassessment of the Unique Mode of Binding between Angiotensin II Type 1 Receptor and Their Blockers
While the molecular structures of angiotensin II (Ang II) type 1 (AT1) receptor blockers (ARBs) are very similar, they are also slightly different. Although each ARB has been shown to exhibit a unique mode of binding to AT1 receptor, different positions of the AT1 receptor have been analyzed and computational modeling has been performed using different crystal structures for the receptor as a t...
BACKGROUND The purpose of this study was to examine the emergency physician (EP) practice of prescribing prophylactic antibiotics for patients with oral lacerations. A secondary outcome measure was the infection rate of those who were or were not prescribed antibiotics. METHODS The study was a retrospective chart review of 323 patients who presented to a large urban emergency department (ED) ...
The present study was designed to investigate the effect of supplementing of protein additives (PA) in forms of 10% ovine amniotic fluid (OAF), 10% fetal bovine serum (FBS) and 10% sheep serum (SS), individually to culture media (TCM-199 or RPMI-1640) on in vitro nuclear maturation (IVM) of sheep oocytes. In addition, the effect of seasonal variations on the yield and quality of recovered sheep...
INTRODUCTION.................................................................. 186 GENERAL PROPERTIES OF THE GENUS MYCOPLASMA.............................. 186 Definition.................................................................... 186 Taxonomy.................................................................... 187 Relationship of Mycoplasmas to L Forms......................................
The catalytic subunit of cAMP-dependent protein kinase (cAPK) is susceptible to inactivation by a number of thiol-modifying reagents. Inactivation occurs through modification of cysteine 199, which is located near the active site. Because cysteine 199 is reactive at physiological pH, and modification of this site inhibits activity, we hypothesized that cAPK is a likely target for regulation by ...
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