The mol-ecule of the title compound, C(22)H(26)N(2)O, displays a trans configuration with respect to the C=N double bond. The dihedral angle between the planes of the two aromatic rings is 26.30 (15)°. There is a strong intra-molecular O-H⋯N hydrogen bond between the imine and hydroxyl groups.

In the title compound, C(19)H(14)Cl(2)O(4), intra-molecular C-H⋯O and C-H⋯Cl hydrogen bonds generate S(6) and S(5) ring motifs, respectively. In the crystal structure, inter-molecular C-H⋯O inter-actions between symmetry-related mol-ecules involving two methyl-ene groups and an O atom as a bifurcated acceptor generate an R(2) (1)(6) ring motif. In the mol-ecule, one of the furan rings is rotati...

In the title compound, C(24)H(35)NO(2), the planes of the two aromatic rings form a dihedral angle of 72.76 (4)°. In the crystal, mol-ecules are linked by O-H⋯O and O-H⋯N hydrogen-bond inter-actions, forming an extended two-dimensional framework parallel to the ab plane.

BACKGROUND Reductions in the dose intensity (DI) of adjuvant anthracycline-based chemotherapy in early stage breast cancer are frequently required due to treatment toxicity or poor tolerance, but the implications of a minimal reduction in DI on clinical outcome remain uncertain. PATIENTS AND METHODS Women with stage I-II breast cancer treated with adjuvant adriamycin and cyclophosphamide (AC)...

Culture-dependent and culture-independent approaches were used to determine the relationship between the dehalogenase gene pool in bacteria enriched and isolated on 2,2-dichloropropionic acid (22DCPA) and the environmental metagene pool (the collective gene pool of both the culturable and uncultured microbes) from which they were isolated. The dehalogenases in the pure-cultures isolates, which ...

The role of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes (5-HT2AR, 5-HT2BR, and 5-HT2CR) in acute cocaine-evoked hyperactivity was compared with their contribution to the development and expression of locomotor sensitization upon repeated, intermittent treatment with cocaine (10 mg/kg/day for 5 days) in male Wistar rats. Cocaine-evoked hyperactivity was significantly enhanced b...

1-carboxymethyl-3-methylimidazolium chloride {[cmmim]cl} is utilized as a highly efficient and reusable catalyst for the synthesis of bis(indolyl)methanes by the condensation reaction of indole with arylaldehydes under solvent-free conditions at room temperature. in summary, the presented method have several advantages including simplicity, low cost, generality, efficiency, clean reaction profi...