نتایج جستجو برای: 2 amino benzimidazole
تعداد نتایج: 2673039 فیلتر نتایج به سال:
Benzimidazole derivatives have shown hopeful activity in the treatment of several diseases, for this reason, the synthesis of novel benzimidazole remains a main focus for researchers. This review article summarizes the chemistry of different derivatives of benzimidazole along with their biological activities. The review article also covers the most active benzimidazole derivatives that have sho...
Regular monitoring of benzimidazole resistance status helps in timely implementation of resistance mitigation strategies in farms. Egg hatch assay (EHA) evaluates the ability of benzimidazoles to inhibit or prevent embryonation and hatching of nematode eggs and is the standard in vitro test for detection of benzimidazole resistance. The present study reports detection of benzimidazole resistanc...
Trypanosoma cruzi has a particular cytoskeleton that consists of a subpellicular network of microtubules and actin microfilaments. Therefore, it is an excellent target for the development of new anti-parasitic drugs. Benzimidazole 2-carbamates, a class of well-known broad-spectrum anthelmintics, have been shown to inhibit the in vitro growth of many protozoa. Therefore, to find efficient anti-t...
A fundamental structural feature of benzimidazoles, a group heterocyclic, aromatic compounds, is the fusion six-membered benzene ring with five-membered imidazole moiety. Formic acid, Acetyl chloride, hydrazine hydrate, Benzene-1,2-diol, Glycolic Acid, Benzoyl Methyl Ethyl Benzamide, and other chemicals were utilized in this research study. In study different methods used such as TLC, IR spectr...
Bioassays using pellets of agar, thatch-agar and turfgrass-agar were developed using benzimidazole-sensitive Penicillium expansum, to detect the fungicide methyl 2-benzimidazole carbamate (MBC) which is the major fungitoxic degradation product of benomyl [methyl 1-(butylcarbamoyl)-2-benzimidazole carbamate] in thatch and turfgrass clippings. These bioassays were used to estimate the amount of f...
A new synthesis of 2-oxa-7-azaspiro[3.5]nonane is described. Spirocyclic oxetanes, including 2-oxa-6-azaspiro[3.3]heptane were converted into o-cycloalkylaminoacetanilides for oxidative cyclizations using Oxone® in formic acid. The expanded spirocyclic oxetane successfully gave the [1,2-a] ring-fused benzimidazole. X-ray crystal structure of the resultant new tetracyclic system, 1',2'-dihydro-4...
2-(2-Alkoxycarbonyl-1-arylamino-1-propenyl)benzimidazolium and 5-(2-alkoxycarbonyl-1-arylamino-1-propenyl)triazolium salts were synthesized in good yields from the reaction of benzimidazole and triazole carbenes with ketenimines. Upon treatment with a base, both salts were converted into novel 1,3-dipoles which underwent [3+2] cycloaddition reactions with electron-deficient alkynes and allenes ...
Mixed crystals of 1-(4-chlorophenylsulfonyl)-2,5-dimethyl-1 H -benzimidazole and 1-(4-chlorophenylsulfonyl)-2,6-dimethyl-1 (ratio 0.707:0.293; two molecules in the asymmetric unit), 0.707C 15 13 ClN 2 O S·0.293C S, ( I ), 2- n -butyl-1-(4- tert -butylphenylsulfonyl)-5-chloro-1 -butylphenylsulfonyl)-6-chloro-1 [ratio 0.731 (2):0.269 (2); one molecule unit], 0.731C 21 25 S·0.269C II were obtained...
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