OBJECTIVES The purpose of this study was to evaluate the impact of moderate-or-less functional tricuspid regurgitation (TR) treatment on the clinical outcome of patients with mitral valve (MV) surgery. METHODS From October 2001 to January 2005, 167 patients in our hospital with MV surgery and without organic tricuspid valve (TV) disease or pulmonary hypertension (PH) showed moderate-or-less f...

In the first half of winter 2020/21, China has experienced an extremely cold period across both northern and southern regions, with record-breaking low temperatures set in many stations China. Meanwhile, a moderate La Niña event which exceeded oceanic atmospheric thresholds began August 2020 few months developed into its mature phase, just prior to 2020/21 winter. this report, mid?high-latitude...

All guidelines on major depressive disorder (MDD) and anxiety disorders recommend pharmacotherapy and/or psychological treatment for moderate to severe disease. The aim of this cross-sectional study was to investigate treatment inadequacy, both pharmacological and psychological, in a large naturalistic cohort of subjects with MDD and anxiety disorders from the Netherlands Study of Depression an...

This study modelled the economic impact of mirtazapine, compared to amitriptyline and fluoxetine, in the management of moderate and severe depression in the UK, as well as the costs related to discontinuation of antidepressant treatment. Decision models of the management of moderate and severe depression were developed from clinical trial data, resource use obtained from interviews with general...

BACKGROUND This study was aimed to investigate the prevalence of dental anxiety in a population of patients with Borderline Intellectual Functioning (BIF) and patients with mild and moderate intellectual disability (ID), and how dental anxiety correlated with their age and gender. METHODS The sample was made of 700 patients, 287 females and 413 males, 6-to-47 years old, either with borderline...

AIMS In our study, we investigated the impact of papillary muscle systolic dyssynchrony (DYS-PAP) and the configuration of mitral leaflets in the prediction of significant functional mitral regurgitation (MR) with two-dimensional (2D) speckle-tracking strain analysis in non-ischaemic dilated cardiomyopathy (DCM) patients with sinus rhythm. METHODS Thirty-six non-ischaemic DCM patients (left v...

Abstract Residential treatment is a common option for individuals with moderate to severe substance use disorders. In cohort of who accessed residential treatment, we investigated client demographic, use, mental health, and psychological predictors completion. Participants were retrospective 1056 (15–69 years) admitted facilities across Queensland, Australia, from January 2014 December 2016. Pa...

(ESCC) is a deadly disease with a 5-year survival of only 10% [1]. Because of the absence of early symptoms, ESCC is commonly diagnosed at an advanced stage. Thus, the development of new prevention and therapeutic approaches are urgently needed. Dietary zinc (Zn) deficiency (ZD), a significant public health issue affecting 31% of the global population [2], is associated with an increased risk o...