By developing and maintaining mutually rewarding relationships with selected groups of patients and other partners, pharmacists can more effectively market pharmacy services.

The title compound, C(31)H(50)O, a tetra-cyclic triterpene, was isolated from Ainsliaea henryi. The mol-ecule contains a three-membered ring, a five-membered ring, which exhibits an envelope conformation, and three six-membered rings, which adopt chair conformations.

Emerging evidence suggests that autophagic modulators have therapeutic potential. This study aims to identify novel autophagic inducers from traditional Chinese medicinal herbs as potential antitumor agents. Using an image-based screen and bioactivity-guided purification, we identified alisol B 23-acetate, alisol A 24-acetate, and alisol B from the rhizome of Alisma orientale as novel inducers ...

background: the 4t1 cells tumor growth and metastatic pattern in balb/c mice very closely mimic human breast cancer. these herbal remedies used in traditional folk medicine have been the source of many medically beneficial drugs. the aim of the current study was to evaluate the anti-proliferative activity of the asafoetida, ginseng and fennel ethanolic extracts on mouse breast cancer 4t1 cell-l...

In June 2013, Mount Fuji was nominated as a UNESCO World Heritage site. Subsequently, a new system was piloted encouraging climbers to make a donation of 1000 JPY to help improve environmental conservation. This research is part of a larger study from 2008 to 2014 monitoring the characteristics and behaviour of Fuji climbers. Specifically, this paper investigates Japanese and international clim...

two rare cases of extra-articular diffuse variant giant cell tumor of the tendon sheath are presented, at the elbow of a 68-year-old female and the foot of a 56-year-old male. both patients presented with a palpable masses and marginal excision was performed; histological sections confirmed the diagnosis of extra-articular giant cell tumor. no adjuvant therapy was administered. at the last foll...

Background: The aim of the study was to determine mechanism Moringa oleifera-induced apoptosis in HeLa cells. cells over-express cyclin E and B1, abrogate G0-G1 G2-M cell cycle arrest, promoting tumorigenesis. Cyclin E, E2F1 telomerase expression, caspase-3 -7 activation were assessed after 24-treatment with M. oleifera leaf fractions. Material methods: Apoptosis through caspase-7 determined qu...

Complex molecular mechanisms control B-cell fate to become a memory or a plasma cell. Interleukin-24 (IL-24) is a class II family cytokine of poorly understood immune function that regulates the cell cycle. We previously observed that IL-24 is strongly expressed in leukemic memory-type B cells. Here we show that IL-24 is also expressed in human follicular B cells; it is more abundant in CD27 me...

objective: hexavalent chromium [cr (vi)] compounds are well-known environmental contaminants  generated from industrial processes. several studies have reported the harmful effects of cr (vi) on different organs, however, little is known about neurotoxic effects of cr (vi). the aim of this study is to investigate the toxic effects of cr (vi) on pc12 cells. methods: pc12 cells were cultured foll...

Today we examine the zig-zag product introduced by Reingold, Vadhan, and Wigderson [2] and Capalbo, Reingold, Vadhan, and Wigderson [1]. The product leads to a remarkable constructioon of expander graphs needed in the Spiser-Spielman code. In addition, their works introduce a probabilistic viewpoint of expansion. In previous literature, the spectral techniques are used to analyze the expansion ...