BACKGROUND MicroRNA-33a and -b (miR-33a/b) have been revealed to be posttranscriptional regulators of HDL metabolism. Xuezhikang (XZK) is a marked natural HDL-raising polypill. We aim to evaluate the effects of XZK on the expression of circulating miR-33a/b in patients with low plasma HDL-C levels. METHODS A total of 42 participating patients with low baseline levels of HDL cholesterol were a...

OBJECTIVE The purpose of this study was to investigate whether pregnancy induces increased insulin production as a marker of improved beta-cell function in women with long-term type 1 diabetes. RESEARCH DESIGN AND METHODS This was a prospective study of 90 consecutive pregnant women with type 1 diabetes. At 8, 14, 21, 27, and 33 weeks blood samples were drawn for measurements of A1C, C-peptid...

BACKGROUND Anti-interleukin-33 (anti-IL-33) and anti-Siglec-F antibodies have potent anti-allergic effects on murine allergic asthma and rhinitis and induce eosinophil apoptosis. OBJECTIVE We aimed to determine whether post-sensitization with anti-IL-33/anti-Siglec-F treatments exhibited more potent effects compared to individual treatments in a murine allergic asthma model. MATERIAL AND ME...

done so in 1980–1984.3 Since the condom is widely available and does not require a visit to a provider, the rapid increase in its use at first intercourse suggests that young women and men may be relying less on family planning providers as their first source of protection against pregnancy. An analysis of 1982 NSFG data determined that 17% of sexually active women aged 15–24 in 1982 had visite...

The theory of collocational networks adopts a textual definition of the phenomenon ofcollocation in an electronic corpus. The networks move out from a central node exploring thesignificant word associations of both base and collocate. This is done by measuring statisticalsignificance using mutual information. Working within a carefully-constructed corpus based on adiscourse comm...

and other STDs. Men in their 20s are more likely to be sexually active and are less likely to use condoms than teenagers.4 Their high-risk sexual behavior also leads to increased risk for disease: Half of all new HIV infections in the United States are among people younger than 25,5 and young men aged 20–24 have the highest rate of gonorrhea infection among all male age-groups.6 In contrast to ...

Thermoanaerobacter thermohydrosulfuricus BSB-33 is a thermophilic gram positive obligate anaerobe isolated from a hot spring in West Bengal, India. Unlike other T. thermohydrosulfuricus strains, BSB-33 is able to anaerobically reduce Fe(III) and Cr(VI) optimally at 60 °C. BSB-33 is the first Cr(VI) reducing T. thermohydrosulfuricus genome sequenced and of particular interest for bioremediation ...

The sycamore lace bug, Corythucha ciliata (Say) (Hemiptera: Tingidae), is an important invasive exotic pest of Platanus (Proteales: Platanaceae) trees in China. The objective of this study was to determine the effects of temperature on C. ciliata in the laboratory so that forecasting models based on heat accumulation units could be developed for the pest. Development and fecundity of C. ciliata...