Recent studies of calorie restriction in several organisms demonstrate an increase in mitochondrial activity that is associated with the salutary effects of this dietary restriction regimen. In this Essay, I speculate on how an increase in mitochondrial activity might provide benefit and discuss how diet, mitochondria, and sirtuins might interact in a pathway to slow aging and associated diseases.

Maintaining wheat productivity under the increasing temperatures in South Asia is a challenge. We focused on developing early maturing wheat lines as an adaptive mechanism in regions suffering from terminal heat stress and those areas that require wheat adapted to shorter cycles under continual high temperature stress. We evaluated the grain yield performance of early-maturing heat-tolerant ger...

Prevailing thinking about obesity and related diseases holds that quantifying calories should be a principal concern and target for intervention. Part of this thinking is that consumed calories - regardless of their sources - are equivalent; i.e. 'a calorie is a calorie'. The present commentary discusses various problems with the idea that 'a calorie is a calorie' and with a primarily quantitat...

Excess calorie consumption is associated with metabolic disorders and increased incidence of morbidity. Restricting calorie content, either by daily calorie restriction or intermittent fasting periods, has multiple benefits including weight loss and improved body composition. Previous research has shown that restricting calories in this way can increase longevity and slow the ageing process in ...

AMA Giordano U, Kobiałka J, Pilch J. LOW-CALORIE SWEETENERS IN OBESITY TREATMENT: A PROMISE FOR THE FUTURE?. Health Problems of Civilization. 2023. doi:10.5114/hpc.2023.130646. APA Giordano, U., Kobiałka, J., & Pilch, (2023). https://doi.org/10.5114/hpc.2023.130646 Chicago Ugo, Jakub and Justyna Pilch. "LOW-CALORIE FUTURE?". Harvard MLA Ugo et al. FUTURE?." Civilization, Vancouver

phytate in poultry rations containing rice bran (rb) critically reduce poultry performance while increasing n and p excretion. the objective of this study was to determine whether the anti-nutritive problems associated with higher inclusions of rice bran in poultry rations (up to 40%) could be mitigated with mega doses of phytase. twenty days old male broiler chicks (n=180) in 60 floor pens wer...

1 Motivation Tactical theorem provers or proof planners, such as Clam 4], HOL3], or mega 2] provide proof tactics and/or proof methods to support abstract level proof construction and to improve the communication with the user. Tactics and methods typically abbreviate frequently recurring low level proof patterns. A system like mega 2] is capable of an explicit maintenance of abstract level pro...

For secure communication it is not just sufficient to use strong cryptography with good and strong keys, but to actually have the assurance, that the keys in use for it are authentic and from the contact one is expecting to communicate with. Without that, it is possible to be subject to impersonation or man-in-the-middle (MitM) attacks. Mega meets this problem by providing a hierarchical authen...