background: meningioma is among the most common slow growing central nervous neoplasms, which recurs locally despite the benign histologic features. the aim of this study was to evaluate osteopontin and ki67 expressions in different histologic grades of meningioma in a group of iranian people. methods: in this cross-sectional study, first, the paraffin blocks with the definite pathological diag...

the aim of this study was to prepare a new formula of leishmania major (l. major) crude antigen and evaluate its effect on immune system. for this purpose l. major promastigotes were cultured, harvested, washed, and resuspended in physiologic saline and the suspensions were dispersed in five equal batches. 0.1 ml of various doses of the cocktail antigen were injected intradermaly in three group...

background: the aim of this study was to assess the performance of antigen b (agb) isolated from different echinococcus granulosus intermediate hosts and from different cyst locations for immu­nodiagnosis of human cystic echinococcosis (ce). methods: hydatid cyst fluids were collected from lung and liver cysts of sheep, liver cysts of goats, lung cysts of camels and cattle, and liver cysts of h...

Hydatid cyst fluid has been used as a source of antigen for the serodiagnosis of Echinococcus granulosus infection. Due to cross-reactions with antigens shared by other helminthes, the specific antigen from hydatid cyst fluid was purified by many workers. We used a relatively simple technique for purification of specific antigen from sheep hydatid cyst fluid. Isopycnic ultracentrifugation w...

We have previously shown that antigen-induced eosinophil recruitment into the tissue of sensitized mice is mediated by CD4+ T cells and IL-5. To determine whether the induction of oral tolerance down-regulates antigen-induced eosinophil recruitment into the tissue, we studied the effect of oral administration of a protein antigen on antigen-induced eosinophil infiltration in the trachea of sens...

BACKGROUND Polymorphonuclear neutrophils (PMNs) were originally described as short lived and terminally differentiated phagocytes that contribute only to the innate immune response. Some studies of PMNs cytokine production and expression of numerous cell surface proteins has suggested that PMNs are likely to influence adaptive responses and may satisfy the criteria of antigen presenting cells. ...

background : echinococcosis or hydatidosis is a chronic, zoonotic worldwide infection caused by the larval stage of the dog taeniid tapeworm echinococcus granulosus. vaccination has been considered as one of the ways to prevent of hy-datidosis in recent decades. the aim of this study was to construct a pcdna3.1 eukaryotic expression vector contain-ing the subunit 8-kda antigen b (hyd1) of e. gr...

in addition to ultrasonographic monitoring of folliculogenesis, urinary luteinizing hormone testing, luteal phase endometrial biopsy, serum antiphospholipid antibodies, etc., immunologic tests are recently being used to evaluate reproductive disorders. in this study, sharing of hla-a, b, c and dr antigens and the presence of antipaternal cytotoxic antibody (apca) was assessed using microcytotox...

background: breast cancer is the most common cancer in women. prostate‑specifc antigen  (psa) is a marker of prostate gland malignancy, which has been considered in cases with breast cancer in recent years. the goal of this study was to determine total and free psa levels in cases with malignant and benign breast lesions. methods:   in  this case–control study, ninety women with histological pr...