The binding curves of histones H1 and H5 to chromatin in nuclei have been determined by a novel method which utilises the differential properties of free and bound histones on cross-linking with formaldehyde. The dissociation is thermodynamically reversible as a function of [NaCl]. The binding curves are independent of temperature over the range 4 degrees - 37 degrees C and independent of pH ov...

Measurements of the cross section σ(xIP , β,Q 2) for diffractive deep inelastic scattering (DIS) processes of the type ep → eXp by H1 at HERA have reached high precision [1]. Here, Q2 is the photon virtuality, xIP is the longitudinal momentum fraction of the diffractive exchange with respect to the proton and β = x/xIP is the exchange’s longitudinal momentum fraction of the quark which couples ...

Cetirizine is a highly efficacious and long acting second generation H1 receptor antagonist indicated for the treatment of allergic diseases. It is a racemate mixture composed of equal amounts of Sand R-enantiomers, and the R-enantioner, levocetirizine, carries the majority of the histamine H1-receptor-blocking activity. Recently, levocetirizine formulation has been introduced in India for the ...

where C is some constant depending only on (M, g), and k. He also announced in the same paper the same result for general manifolds, without the locally conformally flat assumption. The proof of this claim has not been made available. For general manifolds of dimension n = 3, a proof was given by Li and Zhu in [73]; while for n = 4, a combination of the results of Li and Zhang [70] and Druet [4...

The separation and purification of histone H1 from the sperm of the sea-urchin Sphaerechinus granularis is described. Physical studies were used to compare this histone H1 molecule with H1 histones from other species. C.d. and 270 MHz n.m.r. spectroscopy indicate that, despite significant compositional differences from other sea-urchin sperm H1 histones, their secondary and tertiary structures ...

To analyze the mechanism by which histone H3 phosphorylation occurs specifically during mitosis, the effect of H1 on mitosis-specific H3 phosphorylation (Ser-10) was investigated in nucleosomes. H1 interaction with H1-depleted nucleosomes suppressed H3 phosphorylation including Ser-10 by approximately 50%. However, H1 interaction with DNA-free histone octamers failed to suppress H3 phosphorylat...

household cleaning agents (such as Formula 409 or even plain water) were used; however, dishwashing liquid left Ara h1 on 4 of 12 tables (possibly by leaving a film). Six schools were assessed without special prior preparation (2 used peanut-free tables/preparation areas, and 1 was totally peanut-free). Of the 6 preschools and schools evaluated, Ara h1 was found on 1 of 13 water fountains (130 ...

BACKGROUND Mother-to-child transmission (MTCT) is the main cause of HIV-1 infection in children worldwide. Given that the C-type lectin receptor, dendritic cell-specific ICAM-grabbing non-integrin-related (DC-SIGNR, also known as CD209L or liver/lymph node-specific ICAM-grabbing non-integrin (L-SIGN)), can interact with pathogens including HIV-1 and is expressed at the maternal-fetal interface,...

The formation constants of UO2SO4 (aq), UO2(SO4)2(2-), and UO2(SO4)3(4-) were measured in aqueous solutions from 10 to 75 degrees C by time-resolved laser-induced fluorescence spectroscopy (TRLFS). A constant enthalpy of reaction approach was satisfactorily used to fit the thermodynamic parameters of stepwise complex formation reactions in a 0.1 M Na(+) ionic medium: log 10 K 1(25 degrees C) = ...

B7-H1 encompasses a recently discovered cell surface glycoprotein within the B7 family of T-cell co-regulatory molecules. B7-H1 expression can be induced on activated T lymphocytes and is normally expressed by macrophage lineage cells. In addition, some human tumors acquire the ability to aberrantly express B7-H1. Tumor-associated B7-H1, as well as B7-H1 on activated lymphocytes, has been shown...