1 2 Christine M. Kiely, Samuel Marguerat, Jennifer F. Garcia, Hiten D. Madhani, Jürg Bähler, 3 and Fred Winston 4 5 1. Department of Genetics, Harvard Medical School, Boston, MA 02115, USA 6 2. Department of Genetics, Evolution & Environment and UCL Cancer Institute, University 7 College of London, London WC1E 6BT, UK 8 3. Department of Biochemistry and Biophysics, University of California at S...

Stimulation of death receptors by agonists such as FasL and TNFalpha activates apoptotic cell death in apoptotic-competent conditions or a type of necrotic cell death dependent on RIP1 kinase, termed necroptosis, in apoptotic-deficient conditions. In a genome-wide siRNA screen for regulators of necroptosis, we identify a set of 432 genes that regulate necroptosis, a subset of 32 genes that act ...

We describe the treatment of three boys with cavernous lymphangioma of the legs. The suggested guidelines for treatment are extensive surgical resection, although complete resection is usually impossible, and approximately two weeks after the operation aspiration of serous fluid which has accumulated at the operation site, followed by injection of OK-432 (Picibanil). There was pyrexia and local...

INTRODUCTION 425 DEFINING PLAY 426 THEORIES OF PLAY 428 Piaget 428 Vygotsky 429 VARIETIES OF PLAY AND THEIR DEVELOPMENTAL COURSE 430 Sensorimotor and Object Play 430 Physical or Locomotor Play 430 Rough-and-Tumble Play 431 Exploratory Play 431 Construction Play 432 Symbolic Play 432 Summary 433 CONTEMPORARY ISSUES IN PLAY RESEARCH 433 Pretend Play and Theory of Mind 433 Symbolic Understanding 4...

Ksenia V. Melchakova, Bosniya i Gertsegovina v rossiyskoy obshchestvenno-politicheskoy zhizni 1856–1875 gg. [Bosnia and Herzegovina in Russian Social Political Life, 1856–75], Indrik Moscow 2019), 432 pages, ISBN 978-5-91674-537-5.

Reseña de: "(Des)cortesía, actividades de imagen e identidad" (Coords.) (2020) González-Sanz, Marina, Catalina Fuentes Rodríguez y Ester Brenes Peña. Sevilla: Editorial Universidad Sevilla, 432 pp. ISBN: 978-84-472-3020-4.