The enemy of my enemy is my friend. This proverb underlies the rationale to use viruses that specifically attack bacteria (that is bacteriophages, or phages for short) to treat bacterial infections. On paper, phages are the quintessential antibiotic. They can self-adjust their dose, they are species-specific in their target, they counter resistance through evolution, they have minimal side effe...

Gene flow from domesticated plants to free-growing relatives was a rather trivial issue before the advent of transgenic crops. Gene flow into crops was relatively more important, especially to plant breeders trying to introduce new genes in a crop, or to breeders and seed growers wanting to ensure the genetic purity of a cultivar. Genes can now be transferred from bacteria, or potentially any p...

Rationale—MicroRNA miR145 has been implicated in vascular smooth muscle cell differentiation, but its mechanisms of action and downstream targets have not been fully defined. Objective—Here, we sought to explore and define the mechanisms of miR145 function in smooth muscle cells. Methods and Results—Using a combination of cell culture assays and in vivo mouse models to modulate miR145, we chara...

Mid-infrared (MIR, 2 6 μm wavelength) transparent metal oxides are attractive materials for planar integrated MIR photonic devices and sensing applications. In this report, we present reactive sputtering deposited ZrO2-TiO2 (ZTO) thin films as a new material candidate for integrated MIR photonics. The material structure and optical properties were systematically studied as a function of Ti conc...

Open AccessCCS ChemistryRESEARCH ARTICLE15 Jun 2021Helical Conformation Tunability via Hydrogen Bonding in Supramolecular Frameworks Zhijie Xue†, Fuwei Gan†, Hong Liu†, Chengshuo Shen, Huibin Qiu, Bo Yang and Ping Yu Xue† School of Physical Science Technology, ShanghaiTech University, 201210 Shanghai †Z. Xue, F. Gan, H. Liu contributed equally to this work.Google Scholar More articles by author...

The technique of divergent beam X-ray (Kossel) diffraction is being used for determination of local lattice orientations and lattice distortions (elastic strains). The Kossel patterns are recorded in a scanning electron microscope using a digital camera. The advancement in automation of the of the system relies on computerized interpretation of the Kossel patterns. The paper reports on a packag...