OBJECTIVE To evaluate whether the addition of intravenous (i.v.) dexamethasone to standard emergency department (ED) benign headache therapy would reduce the incidence of headache recurrence at 48-72 hours. METHODS This randomized, double-blind, placebo-controlled clinical trial of adult patients presenting with the chief complaint of headache was conducted in the ED of 2 academic, urban Leve...

The effect of a juvenile hormone (JH) mimic R394 (ethyl 9-cyclohexyl-3, 7-dimethy l-2, 4-nonadienoate) applied topically on the abdominal tergum of silkworm (Bombyx mori L.) after the fourth ecdysis has been studied. JH R394 ranging from 1.0, 0.1, 0.01 μl / larva was applied at 48, 72 and 96 hours of V instar larva that was improved the cocoon weight, shell weight and shell ratio etc. The most ...

BACKGROUND AND OBJECTIVES Current chemotherapies of cutaneous leihmaniasis have faced to some problems and limitations; Development of new leishmanicidal drugs from different sources like herbal plants, are crucially important. The objective of the present study was evaluation of in vitro activity of Alkanna frigida extracts in comparison with glucantime against Leishmania major. MATERIALS AN...

background: oxidative stress reflects an imbalance between the reactive oxygen species (ros) and a biological system's ability to readily detoxify the oxidative agents. disturbances in the normal redox state of cells can cause toxic effects through production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and dna. objectives: the purpose ...

The possible role of insulin-like growth factors (IGFs) and their receptors (IGFRs) in the pathogenesis of diabetic embryopathy was investigated. Sexually mature female ICR mice of 6-8 weeks old were made diabetic by a single intraperitoneal injection with 200 mg/kg streptozotocin ten days prior to mating. Fallopian tubes and uterine tissues were obtained from the superovulated diabetic and nor...

BACKGROUND While most trials of thoracic paravertebral nerve blocks (TPVB) for breast surgery show benefit, their effect on postoperative pain intensity, opioid consumption, and prevention of chronic postsurgical pain varies substantially across studies. Variability may result from use of different drugs and techniques. OBJECTIVES To examine the use of TPVB in breast surgery, and to determine...

The cardio-protective effects of neutrophil depletion or inhibition of neutrophil activation early in the course of myocardial reperfusion has been established. Whether these treatments would be effective during extended periods of reperfusion has not been ascertained. Open-chest anesthetized dogs were subjected to left circumflex artery (LCX) occlusion for 90 minutes followed by 72 hours of re...

Background: Several studies have shown that leukemia inhibitory factor (LIF) is one of the most important cytokinesparticipating in the process of embryo implantation and pregnancy, while, the role of this factor on vascular endothelialfactor-A (VEGF-A), as one of the most important angiogenic factor, has not been fully investigated yet. The aimof this study was to evaluate th...

STUDY DESIGN This is a prospective randomized cohort study. PURPOSE We intended to evaluate the efficacy of a 48 hour antibiotic microbial prophylaxis (AMP) protocol as compared with a 72 hour AMP protocol. OVERVIEW OF LITERATURE The current guideline for the prevention of surgical site infection (SSI) suggests the AMP should not exceed 24 hours after clean surgery like spinal surgery. But ...