Abstract Inspired by the fully heavy tetraquark states reported LHCb, ATLAS and CMS Collaborations, we perform a systematical investigation of low-lying pentaquark systems composed charm bottom quarks (anti-quark) in chiral quark model. With help channel-coupling, obtain several candidates, which are $$cccc\bar{b}$$ c<...

The aim of this study was to assess the results of 5-year experience with minimally invasive operation without medial incision and resection cartilages for correction of pectum excavatum. From 2000 we made in our Hospital minimally invasive technique for the correction of pectus excavatum. 75 patients were treated by minimally invasive technique. A convex steel bar is inserted under the sternum...

BACKGROUND We tested the hypothesis that action potential duration (APD) restitution of normal ventricular muscle cells is different during double premature stimuli (S3) compared with a single premature stimulus (S2). We propose a possible ionic mechanism for such a difference. METHODS AND RESULTS Action potentials and isometric tension were recorded simultaneously from isolated canine right ...

The bar-headed goose flies over the Himalayan mountains on its migratory route between South and Central Asia, reaching altitudes of up to 9,000 m. We compared control of breathing in this species with that of low-altitude waterfowl by exposing birds to step decreases in inspired O(2) under both poikilocapnic and isocapnic conditions. Bar-headed geese breathed substantially more than both greyl...

High-entropy alloys (HEAs), recently emerging alloy materials with numerous excellent performances, may have a wide application prospect in impact engineering. However, previous research regarding the mechanical behavior of HEAs has primarily focused on quasi-static testing, whereas dynamic at high strain rates remains elusive. In this paper, unusual simultaneous strength-plasticity enhancement...

Stimulated by the meson-baryon molecular interpretations of $P_c$ states ($P_c(4312)/P_c(4440)/P_c(4457)$), we systematically study interactions between an $S-$wave charm-strange baryon $\Xi_c^{(\prime,*)}$ and anti-charmed meson $\bar{D}^{(*)}$ in a coupled channel analysis. Effective potentials for $\Xi_c^{(\prime,*)}\bar{D}^{(*)}$ one-boson-exchange model can be related to those $\Sigma_c^{(...

Pichia pastoris is a widely used host for the production of heterologous proteins. In this case, high cell densities are needed and oxygen is a major limiting factor. The increased air pressure could be used to improve the oxygen solubility in the medium and to reach the high oxygen demand of methanol metabolism. In this study, two P. pastoris strains producing two different recombinant protein...

The replacement in the diet of refined carbohydrate and fat with fibre and protein has been shown to promote satiety and improve glucose and insulin profiles. It is less clear whether the macronutrient composition of individual foods such as snacks have any meaningful impact on metabolic parameters and satiety. We examined if the consumption of higher protein higher fibre snack bars would resul...

Oligonucleotides targeting M5 muscarinic receptor mRNA were infused for 6 d into the ventral tegmental area of freely behaving rats trained to bar-press for lateral hypothalamic stimulation. The bar-pressing rate was determined at a range of frequencies each day to evaluate the effects of infusions on reward. M5 antisense oligonucleotide (oligo) infusions increased the frequency required for ba...