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We report an octave-spanning coherent supercontinuum (SC) fiber laser with excellent noise and polarization properties. This was achieved by pumping a highly birefringent all-normal dispersion photonic crystal compact high-power ytterbium femtosecond at 1049 nm. system generates ultra-flat SC spectrum from 670 to 1390 nm power spectral density higher than 0.4 mW/nm extinction ratio of 17 dB acr...
PURPOSE To assess the 3-year clinical outcomes of toric phakic intraocular lens (Visian ICL™; STAAR Surgical) implantation for moderate to high myopic astigmatism. METHODS This retrospective study evaluated fifty eyes of 28 patients who underwent toric ICL implantation for the correction of moderate to high myopic astigmatism and who regularly returned for postoperative examination. Before, a...
Maria Domenica Cappellini, Alan Cohen, Antonio Piga, Mohamed Bejaoui, Silverio Perrotta, Leyla Agaoglu, Yesim Aydinok, Antonis Kattamis, Yurdanur Kilinc, John Porter, Marcello Capra, Renzo Galanello, Slaheddine Fattoum, Guillermo Drelichman, Carmelo Magnano, Monica Verissimo, Miranda Athanassiou-Metaxa, Patricia Giardina, Alexandra Kourakli-Symeonidis, Gritta Janka-Schaub, Thomas Coates, Christ...
Photoreactive psoralens can form interstrand crosslinks (ICLs) in double-stranded DNA. In eubacteria, the endonuclease UvrABC plays a key role in processing psoralen ICLs. Psoralen-modified triplex-forming oligonucleotides (TFOs) can be used to direct ICLs to specific genomic sites. Previous studies of pyrimidine-rich methoxypsoralen-modified TFOs indicated that the TFO inhibits cleavage by Uvr...
Although blood transfusions are important for patients with anemia, chronic transfusions inevitably lead to iron overload as humans cannot actively remove excess iron. The cumulative effects of iron overload lead to significant morbidity and mortality, if untreated. Although the current reference standard iron chelator deferoxamine has been used clinically for over four decades, its effectivene...
Under 5 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 597 6.3 5 to 9 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 636 6.8 10 to 14 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 707 7.5 15 to 19 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 788 8.4 20 to 24 years . . . . . . . . . . . . . . . . . . . . ....
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