Flattening filter-free (FFF) beams are available on an increasing number of commercial linear accelerators. FFF beams have higher dose rates than flattened beams of equivalent energy which can lead to increased efficiency of treatment delivery, especially in conjunction with increased FFF beam energy and arc-based delivery configurations. The purpose of this study is to quantify and assess the ...

BACKGROUND A challenge preventing routine clinical implementation of Monte Carlo (MC)-based lung SBRT is the difficulty of reinterpreting historical outcome data calculated with inaccurate dose algorithms, because the target dose was found to decrease to varying degrees when recalculated with MC. The large variability was previously found to be affected by factors such as tumour size, location,...

PURPOSE To develop a comprehensive end-to-end test for Varian's TrueBeam linear accelerator for head and neck IMRT using a custom phantom designed to utilize multiple dosimetry devices. PURPOSE To commission a multiple-source Monte Carlo model of Elekta linear accelerator beams of nominal energies 6MV and 10MV. METHODS A three source, Monte Carlo model of Elekta 6 and 10MV therapeutic x-ray...

Objectives: The primary study objective is to determine the tolerability, acute toxicity profile and loco-regional recurrence (LRR) rate, 2 year relapse free survival (RFS) and overall survival (OS) with the use of selective COX-2 inhibitor, Celecoxib, concurrently with chemoradiotherapy (CRT) as adjuvant treatment for locally advanced squamous cell carcinoma (LASCC) of the larynx. Secondary en...

BACKGROUND Our first trial on radiotherapy for painful heel spur published in 2012 comparing the analgesic effect of a standard dose (6 × 1.0 Gy within three weeks) to that of a very low one (6 × 0.1 Gy within three weeks) resulted in a highly significant superiority of the standard dose arm. In the meantime, experimental data have shown that lower single doses in the range of 0.5 - 0.7 Gy migh...

UNLABELLED Patients with heart failure and sinus rhythm undergoing cardiac resynchronization therapy (CRT) require the proper detection of atrial signals and reliable atrial pacing for AV-synchronous ventricular pacing. The study aim was to compare atrial pacing and sensing characteristics in patients with transvenous CRT and patients with standard pacing indications. METHODS The study group ...

OBJECTIVES Dental status, dental treatment procedures and radiotherapy dosage as potential risk factors for an infected osteoradionecrosis (IORN) in patients with oral cancers: Retrospective evaluation of 204 patients treated in two observation periods of approximately ten years each. PATIENTS AND METHODS In group A, 90 patients were treated in the years 1993-2003, in group B 114 patients in ...

Unlike other commercial treatment planning systems (TPS) which model the rounded leaf end differently (such as the MLC dosimetric leaf gap (DLG) or rounded leaf-tip radius), the RayStation TPS (RaySearch Laboratories, Stockholm, Sweden) models transmission through the rounded leaf end of the MLC with a step function, in which the radiation transmission through the leaf end is the square root of...

Medical robotics is an exciting and relatively new field. Robotics plays an important role in medical engineering. Medical robots were initially used in the 1980s, in the field of urology. Robotic arms were developed and used for prostate resection. They can also be highly specialized and assist in diagnosing and treating patients. While there is still much more work to be done, using robots ca...