s | 45 Methods: Gabapentin 10, 30mg/kg; diclofenac 5mg/kg(reference drug), vehicle(saline) were injected intraperitoneally before 100μl of 1% carrageenan administration into the right hind paws of the rats. Paw thickness was measured by a gauge calipers(Vernier Calipers) before (0th hour) and in every hour during 6 hours after induction of inflammation. Paw thickness of treated groups were comp...

s | 45 Methods: Gabapentin 10, 30mg/kg; diclofenac 5mg/kg(reference drug), vehicle(saline) were injected intraperitoneally before 100μl of 1% carrageenan administration into the right hind paws of the rats. Paw thickness was measured by a gauge calipers(Vernier Calipers) before (0th hour) and in every hour during 6 hours after induction of inflammation. Paw thickness of treated groups were comp...

s | 45 Methods: Gabapentin 10, 30mg/kg; diclofenac 5mg/kg(reference drug), vehicle(saline) were injected intraperitoneally before 100μl of 1% carrageenan administration into the right hind paws of the rats. Paw thickness was measured by a gauge calipers(Vernier Calipers) before (0th hour) and in every hour during 6 hours after induction of inflammation. Paw thickness of treated groups were comp...

OBJECTIVE Pfirrmann disc grade is a useful scoring tool for evaluating disc degeneration, but normal values according to aging process has not been elucidated. This study was conducted to identify the prevalence and pattern of whole spine disc degeneration according to ages and gender differences. METHODS Total 653 patients (336 male and 317 female patients, 48.1±58.7 years old) who took whol...

BACKGROUND Gingival overgrowth (GO) is a common side effect of the chronic use of cyclosporine (CsA), an immunosuppressant widely used to prevent rejection in transplant patients. Recent studies have reported elevated levels of specific cytokines in gingival overgrowth tissue, particularly TGF-beta, suggesting that this growth factor plays a role in the accumulation of extracellular matrix mate...

To test the hypothesis that persistent myocardial stunning can lead to hibernating myocardium, 13 pigs were chronically instrumented, and persistent stunning was induced regionally by 6 repetitive episodes of 90-minute coronary stenosis (CS) (30% reduction in baseline coronary blood flow [CBF]) followed by full reperfusion every 12 hours. During the 1st CS, CBF fell from 43+/-2 to 31+/-2 mL/min...

Intrahepatic cholangiocarcinoma (ICC) was differentiated from hepatocellular carcinoma, as defined in the American Joint Committee on Cancer (AJCC) 6th edition staging manual, using the revised staging system described in the AJCC 7th edition staging manual. This study was conducted to analyze the application of the AJCC 6th and 7th edition staging classifications and to evaluate a modified sta...

Background The purpose of this study was validation of the Persian translation of the Swiss Spinal Stenosis Questionnaire in order to be used by Iranian researchers. Methods A total of 104 patients with spinal stenosis diagnosis, who were candidates for operative treatment were entered into the study. The patients completed the translated questionnaire in the 1st and the 7th days of admission...

The purpose of this study was to assess the reliability and validity of a new self-rating scale to measure children's pubertal status without pictorial representations or interviews. The scale is an adaptation of an interview-based puberty-rating scale by Petersen, and included scores for each of five items rating physical development, an overall maturation measure, and a categorical maturation...

The aim is to investigate the analgesic effect of transcranial direct current stimulation(tDCS) on central neuropathic pain(CNP) in spinal cord contusive rat model. Twenty Sprague-Dawley rats(250±50 g, male) were used. Thoracic spinal cord(T10) was contused using New York University(NYU) spinal cord impactor. The animals were randomly assigned to two groups; GroupI: Nontreatment after SCI induc...