Previously undescribed compounds, (R)-4-(4-hydroxyphenyl)-2-butanol 2-O-(6-O-galloyl)-β-D-glucopyranoside (1) and (E)-5-(4-hydroxyphenyl)pent-2-enoic acid (2), together with 20 known compounds (3-22) were isolated from the aerial parts of Calligonum mongolicum. Compound 3 was obtained a natural source for first time, all (1-22) reported time in this plant. The structural elucidation 1 2 perform...

west of China, Nepal and the northeast of India. In Tibet it is popularly known and used in traditional medicine for the treatment of liver diseases, cholic diseases, and dyspepsia. Previously a large amount of lignans have been reported from Herpetospermum caudigerum. In the previous investigation, a ethanol extract of the seeds of Herpetospermum caudigerum showed positive activity in the inhi...

The solution conformations of heparin and de-N-sulphated, re-N-acetylated heparin have been determined by a combination of n.m.r. spectroscopic and molecular-modelling techniques. The 1H- and 13C-n.m.r. spectra of these polysaccharides have been assigned. Observed 1H-1H nuclear Overhauser enhancements (n.O.e.s) have been simulated using the program NOEMOL [Forster, Jones and Mulloy (1989) J. Mo...

curcumin (cur) is the active curcuminoid with many physiological, biochemical, and pharmacological properties. solubility and stability of cur is the limiting factors for realizing its therapeutic potential. bovine β-casein is an abundant milk protein that is highly amphiphilic and self-assembles into stable micellar nanoparticles in aqueous solution. β-casein nanoparticle can solubilize cur mo...

A one-step synthesis of phloretin derivatives 2-11 from phloretin in good to excellent yields is reported. Their structures were characterized by 1H-NMR, 13C-NMR and MS, and the structures of 8 and 11 were determined by X-ray diffraction analysis. A mechanism for the formation of 9-11 is proposed. Compared with the anticancer drug docetaxel, phloretin, phloretin derivatives and phlorizin exhibi...

Abstract Gas condensate diesel fuels, being an excellent resource base, often do not meet modern standards of the cetane number value and content sulfur compounds (SC). Currently, Euro 5 6 (<10 ppm content) motor fuels are produced worldwide. High-quality using hydro desulfurization process. Analysis scientific publications has shown that adsorption is effective method desulphurization, whic...

Aminopterin (AMT) is a kind of universal antineoplastic drugs, but it has severe toxic and side effects, leaving rarely used in clinic. Herein, we found that cucurbit[7]uril (CB[7]) AMT can form stable inclusion complexes, the formation CB[7]-AMT 2:1 supramolecular complex was confirmed by UV-visible absorption spectra, fluorescence 1H NMR, molecular modeling calculations aqueous solution. Bind...

The main goal of this work was to report the synthesis, characterization, and cytotoxicity study a novel copper(II)-sunitinib complex, CuSun. It has been synthesized characterized in solid state solution by different methods (such as DFT, FTIR, Raman, UV-vis, EPR, NMR, etc.). solid-state molecular structure trichlorosunitinibcopper(II), where sunitinib: N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluor...