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word count: 246 Main body word count:3613
“Naše more” 62(4)/2015., pp. 243-246
Electrophoretic and fingerprinting studies in a patient with congenital hemolytic anemia revealed the presence of the unstable hemoglobin K#{246}ln(f398 vat-suet). Examination of parents and siblings gave normal results. Extensive blood group and isozyme studies were consistent with the thesis that Hb K#{246}lndisease in the propositus was the result of a fresh mutation in one of his parent’s g...
TP53 is the most frequently mutated gene in cancer. The p53 protein activates transcription of genes that promote cell cycle arrest or apoptosis, or regulate cell metabolism, and other processes. Missense mutations in TP53 abolish specific DNA binding of p53 and allow evasion of apoptosis and accelerated tumor progression. Mutant p53 often accumulates at high levels in tumor cells. Pharmacologi...
H EMOGLOBIN (Hb) K#{246}ln disease belongs to the group of nonspherocytic hemolytic anemias with a dominant inheritance pattern in which anemia is attributable to instability of the Hb molecule. The molecular pathology of this most common of the unstable Hbs was found to be the result of replacement of valine with methionine at f. 98 (FG 5), causing increased oxygen affinity and instability, po...
01W AND GRONWALL (1) [N 1952 first applied the histochemical method of Hotchkiss for staining carbohydrates. In principle the polysaccharides are oxidized by periodic acid to give polyaldehydes, which yield violet-red compounds with Schiff ‘s reagent, fuchsin sulfite. K#{246}iw’s procedure, although giving excellent results when the glycoprotein was separated electrophoretically on filter paper...
The evidence that proteasomes are involved in the processing of cross-presented proteins is indirect and based on the in vitro use of proteasome inhibitors. It remains, therefore, unclear whether cross-presentation of MHC class I peptide epitopes can occur entirely within phagolysosomes or whether it requires proteasome degradation. To address this question, we studied in vivo cross-presentatio...
768, p. 284, March 1979. 26. Hellddn, L., Hock, J., Comosci, D. A.,and Tinanoff, N.: Unpublished data. 27. R611a, G.: "Inhibition of Adsorption--General Consideration," in: Proc Microbial Aspects of Dental Caries, eds. Stiles, Loesche, and O’Brien. Microbiology Abstracts, 2: Sp Suppl,
A video panorama constructing algorithm based on information from five different types pre-calibrated cameras with partially overlapping fields of view was developed and implemented using the CUDA C language. Distortion compensation, image stitching on the virtual unit sphere surface, and blending procedures are performed for the operator-controlled 1024768 pixels region of interest with 50 fps.
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