Intubating patients with a huge, fixed supraglottic mass causing an obstruction of the glottis is difficult to most anesthesiologists. We attempted awake fiberoptic orotracheal intubation assisted by Glidescope® Videolaryngoscope (GVL) following topical anesthesia with 4% lidocaine spray and remifentanil infusion. The glottis could not be identified by the GVL view. However, by entering toward ...

Introduction Using alpha blockers such as intravenous (IV) lidocaine has been deemed effective in controlling acute pain. Therefore, the current study was designed with the aim of evaluating the efficiency of IV lidocaine in comparison to IV fentanyl in pain management of patients with renal colic in emergency department (ED). Methods In this double blind clinical trial, 18-65 year old patien...

UNLABELLED Nitric oxide (NO), overproduced by activated macrophages, is important in the pathogenesis of various diseases, including septic shock and inflammatory tissue injury, as well as antibacterial host defense mechanisms. We examined the effects of lidocaine on NO production and the expression of inducible NO synthase (iNOS) protein and messenger RNA (mRNA) in activated macrophages. Murin...

Traumatic and/or surgical injury as well as hemorrhage induces profound suppression of cellular immunity. Although local anesthetics have been shown to impair immune responses, it remains unclear whether lidocaine affects lymphocyte functions following trauma-hemorrhage (T-H). We hypothesized that lidocaine will potentiate the suppression of lymphocyte functions after T-H. To test this, we rand...

U.S. beef slaughter facilities are required to use a carcass intervention treatment to reduce contamination by Escherichia coli O157:H7. Very small beef slaughter operators generally are unable to carry out challenge studies to validate intervention treatment effectiveness, and in-plant pathogen challenge studies are not permitted. The objective of this study was to evaluate the effectiveness, ...

INTRODUCTION Methemoglobinemia is a recognized complication of the use of topical anesthetic sprays. The true scope of the problem or the risk with different topical anesthetic sprays and endoscopic procedures is unknown. METHODS We retrospectively identified all cases of methemoglobinemia that occurred in a university affiliated community hospital from 2001 to 2007. RESULTS Eleven cases of...

Objective. The presence of an upper airway foreign body is an emergent, potentially life-threatening situation that requires careful but rapid evaluation and management. Organic or nonorganic material may typically be found in the pyriform sinuses or tongue base or may be aspirated directly into the tracheobronchial tree. We present here an unusual case report of a patient who accidentally inge...

We report a case of a laryngectomized patient who accidentally aspirated a wooden stick through his tracheal stoma in highly unusual circumstances. He was in a habit of cleaning secretions of upper airway with a wooden stick covered with cotton on the tip soaked in olive oil, via tracheostomy. After applying topical aerolized lidocaine spray through the tracheostomy stoma a flexible video-broch...

Fine-needle aspiration (FNA) of inflammatory and neoplastic head and neck masses has become a widely used procedure in otolaryngology-head and neck surgery. Using both subjective (patient perception) and objective (complication rate, accuracy) criteria, this prospective study evaluated patients undergoing FNA with and without anesthesia. Seventy-five patients were enrolled into 1 of 3 study gro...

Objective: Our purpose was to study whether or not intravenous (IV) administration of lidocaine reduces propofol dose requirement as intramuscular (IM) lidocaine in a placebo-controlled manner. Subjects and Methods: Seventy-five adult patients with American Society of Anesthesiologists physical status I and II, aged 20–60 years who were scheduled for surgery under general anaesthesia were inclu...