1. One Way Permutations with Trapdoor We recall the definition of a one-way functions with trapdoor as introduced in lecture 3. We consider a set of one-way permutations {fi:Di→Di} , i∈I⊆{0,1}* where the Di are finite domains, and I is some index set. example: in RSA scheme the functions are { f (N,e):ZN * →ZN }, where N =p .q for primes p,q and e is relatively prime with φ(N). The functions fi...

Teicoplanin is a glycopeptide antibiotic active against most Gram-positive organisms, including methicillinresistant Staphylococcus aureus (MRSA). In animal studies, antibiotics administered more than 3 h after bacterial contamination have no observable effect on the development of wound infection. The lowest rate of surgical wound infection in clean and clean-contaminated surgery, occurs in pa...

Renal clearance (CLR), a major route of elimination for many drugs and drug metabolites, represents the net result of glomerular filtration, active secretion and reabsorption, and passive reabsorption. The aim of this study was to develop quantitative structurepharmacokinetic relationships (QSPKR) to predict CLR of drugs or drug-like compounds in humans. Human CLR data for 382 compounds were ob...