The study was designed to assess the various factors pertaining to alcohol and drug abuse among internees with the help of the youth survey questionnaire developed by the WHO. 22.67% of the males indulged in alcohol abuse atleast once a month. Correspondingly cannabis was abused by 9.33% of the boys which is the most commonly abased drug of addiction, followed by sedatives and tranquilizers.The...

Cocaine was considered incapable of producing dependence in 1980 but was recently proclaimed the drug of greatest national health concern. Recent clinical and preclinical investigations demonstrate that cocaine produces unique abuse and withdrawal patterns that differ from those of other major abused drugs and suggest that long-term cocaine abuse produces neurophysiological alterations in speci...

Cocaine is one of the most commonly abused drugs in the United States. Ingestion of cocaine may result in a wide array of disease processes due to its stimulant properties, contaminants, or to downstream effects, such as myo- cardial infarction, stroke, or cardiac arrest. Pulmonary complaints are common in patients seeking treatment for cocaine-associated medical problems and include acute eosi...

The incidence of acquired immunodeficiency syndrome (AIDS) in the United States has increased rapidly since the first reports in 1981. Highest estimated rates are among single (never-married) men in Manhattan and San Francisco, men and women who have abused drugs intravenously, and persons with hemophilia. Serosurveys among populations at increased risk for AIDS have demonstrated a high prevale...

SCOTT E. BOWEN, Ph.D., is an associate professor and area chair of the Behavioral and Cognitive Neuroscience Program within the Department of Psychology at Wayne State University (WSU). He is also an associate professor in WSU’s Department of Obstetrics and Gynecology. His preclinical research is focused on behavioral pharmacology, behavioral toxicology, and neurobehavioral teratology. He inves...

Numerous abused drugs of the 3,4-methylenedioxymetamphetamine (MDMA; Ecstasy; N-methyl-1-(3,4-methylenedioxyphenyl)-2-propaneamine) type and various alkyl chain- and aromatic ring-substituted isomers give very similar electron ionization (EI) mass spectra. This seriously affects the analysis of especially ring regioisomeric drug variants. Using collision-induced dissociation (CID) (argon) under...

Unethical athletes and their mentors have long arrogated scientific and medical advances to enhance athletic performance, thus gaining a dishonest competitive advantage. Building on advances in genetics, a new threat arises from athletes using gene therapy techniques in the same manner that some abused performance-enhancing drugs were used. Gene doping, as this is known, may produce spectacular...

Abused arylalkylamines fall into two major categories: the indolealkylamines, and the phenylalkylamines: These agents can be further subclassified on the basis of chemical structure. Examples of these agents possess hallucinogenic, stimulant, and other actions. Drug-discrimination techniques have been used to classify and investigate this large family of agents. Such studies have allowed the fo...

met with in Indian practice. The present paper is an effort to collect and expose some of the modern views, without however pretending to enter exhaustively into the subject. The ^Etiology of Glaucoma.?We may pass this heading over with but scant notice, as there is practically no difference of opinion here. All those conditions which disturb the circulation and cause congestion of the venous s...

The use of the street drug methylenedioxymethamphetamine (MDMA), commonly referred to as ecstasy, has become increasingly prevalent amongst teenagers and young adults in the United States and many other parts of the world. While most anesthesiologists are facile with the intricacies of managing patients intoxicated by alcohol, cocaine and narcotics the new "club" drugs present a challenge, espe...