Iron–sulfur clusters (Fe–S or ISC) are essential cofactors that function in a wide range of biological pathways. In mammalian cells, Fe–S biosynthesis primarily relies on mitochondria and involves concerted group evolutionary-conserved proteins forming the ISC pathway. early stage pathway, core complex is required for de novo assembly Fe–S. humans, comprises cysteine desulfurase NFS1, scaffold ...

A case of WPW Syndrome due to parahisian accessory pathway was ablated by the catheter inversion technique. The pathway could not be eliminated by direct femoral approach using repeated high radiofrequeny energy ablation. No pathway potential was seen in the aortic cusps. Instead, it was successfully ablated by curving the ablation catheter underneath the septal leaflet of the tricuspid valve t...