Objective: The objective of the current investigation was to design aceclofenac encapsulated microbeads using gellan gum and linseed blends following ionotropic gelation by trivalent Al3+-ions as cross-linking agent. Methods: Various formulation parameters like polymer-polymer blend (gellan gum), proportion concentration aluminium chloride (i.e., cross-linker) were considered for preparation di...

Zawilla and coworkers developed and validated three sensitive and reproducible methods for quantitatve determination of aceclofenac in pure form and in pharmaceutical formulation. The first method was based on the reaction between the drug via its secondary aromatic amino group and p-dimethylamino cinnamaldehyde (PDAC) in acidified methanol to give a stable coloured complex after heating at 75°...