self-association of alcohols; including ethanol, methanol, cyclopentanol and octanol in separate mixtures with inert solvents have been studied using ft-ir spectroscopy. except for the band at 3640 cm–1 in the ir spectrum of the alcohols which is due to the monomer species, the presence of other bands in the region of stretching vibrational frequencies of oh (3100-3700 cm–1) are attributed to t...

The identification of lysine acetylation of steroid hormone receptors has previously been based on the presence of consensus motif (K/R)XKK. This study reports the discovery by mass spectrometry of a novel progesterone receptor acetylation site at Lys-183 that is not in the consensus motif. In vivo acetylation and mutagenesis experiments revealed that Lys-183 is a primary site of progesterone r...

Post-translational modification of proteins by lysine acetylation plays important regulatory roles in living cells. The budding yeast Saccharomyces cerevisiae is a widely used unicellular eukaryotic model organism in biomedical research. S. cerevisiae contains several evolutionary conserved lysine acetyltransferases and deacetylases. However, only a few dozen acetylation sites in S. cerevisiae ...

Two reaction strategies are developed to promote the highly selective 1,3-isomerization of a variety of allylic alcohols using O3ReOSiPh3 as a catalyst. The first strategy utilizes substrates whose 1,3-regioisomer contains a conjugated alkene, which relies on thermodynamics to obtain high selectivity. The second strategy employs N,O-bis(trimethylsilyl)acetamide as an additive to selectively and...

Polyisoprenoid alcohols, linear polymers of isoprenoid residues are widespread in nature from bacteria to human cells. Their structures, distribution and biogenesis will be highlighted. Membrane localization of polyisoprenoid alcohols within the cell and techniques used for structural elucidation will be presented. Attention will be focused on the biosynthesis of polyisoprenoid alcohols in plan...

although several methods for the preparation of 4o propargyl indole derivatives have been published, this synthetic transformation is complicated by the tendency of 3o propargyl alcohols to form allenium intermediates in acidic media.  it is therefore a challenge to find an efficient method for the c-3 propargylation of indoles with 3° propargylic alcohols.  in this paper we wish to report on t...

Acetylation is a well-established process to improve dimensional properties of wood and resistance fungi attack. This study was carried out due limited studies on the effect acetylation mechanical properties, thermal stability, microstructural aspects wood. Wood blocks, (each 20×20×60 mm) Obeche were acetylated with acetic anhydride at 120 °C for 60, 120, 180, 240 300 minutes. The microstructur...

Mn(II) salen complex immobilized on nano silicagel was prepared by incorporating Mn(II) salen complex into a nanosilica matrix and characterized by TGA, XRD, atomic absorption spectroscopy and was successfully applied as catalyst for the oxidation of alcohols. Oxidation of a series of alcohols in acetonitrile over immobilized Mn(II) salen complex using tetrabutylammonium peroxymonosulfate (TBAO...

Background: Opioid abuse is common in Iran. In recent years, methadone maintenance therapy (MMT) has gained popularity in this country. This study aimed at evaluation concurrent abuse of alcohol in patients under MMT. Methods: A predesigned questionnaire was developed and completed after obtaining verbal consent among 49 subjects under MMT in Kian Rehabilitation Centre during January 2014. Resu...

A comprehensive study of the solution and solvation of linear alcohols (propan-1-ol, butan-1-ol and pentan-1-ol) in ionic liquids (ILs) is presented. The effect of the alkyl chain size of both alcohols and ILs (1-alkyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, [CnC1im][NTf2], ionic liquid series) on the thermodynamic properties of solution and solvation was used to obtain insight i...