The mode of interaction of asbestos fibres with cell membranes is still debatable. One reason is the lack of a suitable and convenient cellular model to investigate the causes of asbestos toxicity. We studied the interaction of asbestos fibres with Xenopus laevis oocytes, using electrophysiological and morphological methods. Oocytes are large single cells, with a limited ability to endocytose m...

Aerial continuum manipulation systems (ACMSs) were newly introduced by integrating a robot (CR) into an aerial vehicle to address few issues of conventional such as safety, dexterity, flexibility and compatibility with objects. Despite the earlier work on decoupled dynamic modeling ACMSs, their coupled still remains intact. Nonlinearity complexity CR make it difficult design ACMS model suitable...

There is recent mounting evidence that nanoparticles may have enhanced toxicological potential in comparison to the same material in the bulk form. The aim of this study was to develop a new method for unmask asbestos nanofibers from Formalin-Fixed, Paraffin-Embedded tissue. There is an increasing amount of evidence that nanoparticles may enhance toxicological potential in comparison to the sam...

Mesothelioma, a malignant cancer of the pleura, is almost exclusively associated with asbestos exposure.1 What will it take to eradicate this highly preventable cancer? Despite the scientific consensus that exposure to asbestos fibres causes deadly diseases, we continue to use asbestos in products designed ostensibly to improve quality of life. For example, asbestos is still used in automobile ...

Mesothelioma, a rare tumor, is highly correlated with asbestos exposure. Mesothelioma, similar to all asbestos-related diseases, is dose/intensity dependent to some degree, and studies showed the risk of mesothelioma rises with cumulative exposures. Multiple processes occur in an individual before mesothelioma occurs. The impact of mesothelioma in the United States has been continuous over the ...

BACKGROUND Construction site supervisors are exposed to many chemicals, dusts, and metals including asbestos. Asbestos is a hazardous chemical that is carcinogenic. Laryngeal cancer is not a rare disease in Korea. The most common causes of this disease are tobacco and alcohol, and representative occupational cause is asbestos. However, up to now, no case of laryngeal cancer induced by asbestos ...

Meurman, L. O., Kiviluoto, R., and Hakama, M. (1974). British Journal ofIndustrial Medicine, 31, 105-112. Mortality and morbidity among the working population of anthophyllite asbestos miners in Finland. A study has been made in Finland of the effects of anthophyllite asbestos on mortality and morbidity of 1 092 asbestos workers first employed at two mines between 1936 and 1969; 95% of workers ...

In spite of hard epidemiological and clinical evidence associating asbestos fibre with asbestosis and cancer, the issue is controversial and likely to remain so. The focus is now shifting to non-occupational exposure, differential risk to various asbestos fibre types and the relatively low level of carinogenicity of the chrysotile form. This creates further space for scientific debate and the o...

Various researchers and agencies recommend different conversion factors for different asbestos exposures. The aim of this study was to develop conversion factors from particles per cm3 (p cm(-3)) to fibres per cm3 (f cm(-3)) and from mg m(-3) to f cm(-3). More than 1000 exposure measurements were available in the Slovenian asbestos-cement factory Salonit Anhovo. Three types of measurement of as...

Cellular mechanisms of asbestos toxicity rely, at least in part, on the chemical composition of these minerals. Iron ions are directly involved in the accepted mechanism of fiber toxicity because they constitute active centers where release of free radicals and reactive oxygen species takes place. Although no current technology is available for the remediation of asbestos polluted sites, the so...