The aim of this work was to evaluate the effect of in vitro alendronate (AD) release behavior through polycaprolactone (PCL) coating on in vivo bone formation using PCL-coated 3D printed interconnected porous tricalcium phosphate (TCP) scaffolds. Higher AD and Ca(2+) ion release was observed at lower pH (5.0) than that at higher pH (7.4). AD and Ca(2+) release, surface morphology, and phase ana...

Mobile agent technology has gained increasing importance in recent years. However, little work has been done in defining notations/languages to capture and model mobile agent applications. This paper presents extensions of UML activity diagrams for modelling mobile agent applications, which capture specific features of mobile agents such as mobility, cloning and communications.

Physical activity shows promise for protection against cognitive decline in older adults with and without Alzheimer's disease (AD). To better understand barriers to adoption of physical activity in this population, a clear understanding of daily and weekly activity patterns is needed. Most accelerometry studies report average physical activity over an entire wear period without considering the ...

Procurement refers to a process resulting in delivery of goods or services within a set time period. The process includes aspects of purchasing, specifications to be met, and solicitation notifications as in the case of Request For Proposals (RFPs). Typically, such an RFP is described in a verbal ad hoc fashion, in English, with tables and graphs, resulting in imprecise specifications of requir...

We analyze photometric data of the active RS CVn–type star HR 1099 for the years 1975–2006 with an inversion technique and reveal the nature of two activity cycles of 15–16 yr and yr duration. The 16 yr cycle is 5.3 0.1 related to variations of the total spot area and is coupled with the differential rotation, while the 5.3 yr cycle is caused by the symmetric redistribution of the spotted area ...

For testing software, test case generation is the most important part. The automation of specification based test case generation needs formal or semi formal specification. As a semiformal modeling, UML is widely used to describe analysis and design specification by both academia and industry. Thus UML models become the sources of test case generation naturally. This paper proposes a method to ...

This paper presents an approach to describe business process in production systems using workflow concepts. In this sense, we define an extension of the UML Activity Diagram called Workflow Activity Diagram (WAD) which applies the C-WF model concepts. The C-Wf model represents the structural and functional enterprise objects involved in the business processes, such as enterprise activities, hum...

A direct use of activity cycle diagram (ACD) model into a simulation execution has a limitation that it does not maximize the power of the widely adopted three-phase rule in the simulation execution of ACD models. This paper presents a key model specification for the simulation execution of the ACD model, named, activity transition table (ATT). The proposed ATT reduces the gap between the ACD (...

A new routing metric for multihop wireless ad hoc networks is presented. The proposed metric is based on the computation of signal-to-noise ratio and path minimization of wireless ad hoc network outage probability in a fading environment. This metric improves the quality of service by reducing the number of dropped packets. Further, by modeling the network with a Trellis diagram and then using ...

Lipids play an important role as risk or protective factors in Alzheimer's disease (AD). Previously it has been shown that plasmalogens, the major brain phospholipids, are altered in AD. However, it remained unclear whether plasmalogens themselves are able to modulate amyloid precursor protein (APP) processing or if the reduced plasmalogen level is a consequence of AD. Here we identify the plas...