We reviewed the records of 151 patients diagnosed with American cutaneous leishmaniasis (ACL) from 1993 to 2009 in the municipality of Japura, Paraná, Brazil. Gender, age, occupation, place of residence, location of lesions, type and number of lesions were analyzed. The prevalence rate of ACL was 11.5/10,000 hab, of which 84.7% were male, 58.3% lived in rural area and 49.0% were farmers. The mo...

This study was designed to evaluate the effectiveness of zinc sulphate both in vitro and in an animal model against both strains of old world cutaneous leishmaniasis. The in vitro sensitivities of promastigotes and axenic amastigotes of both Leishmania major and L. tropica to zinc sulphate was determined, the LD50 calculated and compared to the standard treatment for cutaneous leishmaniasis pen...

We present a case of a child with Leishmania infantum cutaneous leishmaniasis unresponsive to 2 courses of intravenous liposomal amphotericin B, a treatment failure that has not been reported in this Leishmania species. The patient responded to topical imiquimod and had no relapse. We review the literature on the treatment failure of liposomal amphotericin B for cutaneous leishmaniasis.

American cutaneous leishmaniasis (ACL) is a focal disease whose surveillance and control require complex actions. The present study aimed to apply integrated tools related to entomological surveillance, environmental management, and health education practices in an ACL-endemic area in Rio de Janeiro city, RJ, Brazil. The distribution of the disease, the particular characteristics of the localit...

Whether cutaneous leishmaniasis exists in China is a problem of concern in the international field of parasitology. Zhang and Hu (1983) found a girl aged 15 with mild hepatomegaly and cutaneous ulcer on her right cheek in Shawan County of Xinj­ iang; Leishmania was detected in both the exudates and biopsy tissues, but the parasite was not detected in a bone marrow smear. Notwithstanding the fac...

The antileishmanial efficacy of the reference drug N-methylglucamine antimoniate (Glucantime) was evaluated in groups of rhesus monkeys with acute and chronic Leishmania (Viannia) braziliensis cutaneous infection. The therapeutic responses in experimental animals to either a low dose (5 mg/kg body wt/day for 28 days) or a routine dose (20 mg/kg/day for 28 days) of pentavalent antimony were simi...

Leishmaniasis is a protozoan zoonotic disease that is seen in Cutaneous, subcutaneous and visceral forms. The disease is transmissible via sand flies between humans and many animals, including rodents and dogs. The aim of the present study was to determine the prevalence of Cutaneous leishmaniasis in Sabzevar over four years. Information on all patients from the Sabzevar Health Center who had b...

Leishmaniasis is a protozoan zoonotic disease that is seen in Cutaneous, subcutaneous and visceral forms. The disease is transmissible via sand flies between humans and many animals, including rodents and dogs. The aim of the present study was to determine the prevalence of Cutaneous leishmaniasis in Sabzevar over four years. Information on all patients from the Sabzevar Health Center who had b...

Here we report the case of a patient with cutaneous leishmaniasis, who was referred to our clinic in Yazd, Iran. On examining the patient, who was a housekeeper, we found a small plaque in the palmoplantar region due to cutaneous leishmaniasis. She had not any history from an identical case in this patient. After treatment, the lesions improved.